Circadian gene variants in diseases
P Gršković, P Korać - Genes, 2023 - mdpi.com
The circadian rhythm is a self-sustaining 24 h cycle that regulates physiological processes
within the body, including cycles of alertness and sleepiness. Cells have their own intrinsic …
within the body, including cycles of alertness and sleepiness. Cells have their own intrinsic …
A targeted epigenetic clock for the prediction of biological age
Epigenetic clocks were initially developed to track chronological age, but accumulating
evidence indicates that they can also predict biological age. They are usually based on the …
evidence indicates that they can also predict biological age. They are usually based on the …
Association of rs3027178 polymorphism in the circadian clock gene PER1 with susceptibility to Alzheimer's disease and longevity in an Italian population
MG Bacalini, F Palombo, P Garagnani, C Giuliani… - GeroScience, 2022 - Springer
Many physiological processes in the human body follow a 24-h circadian rhythm controlled
by the circadian clock system. Light, sensed by retina, is the predominant “zeitgeber” able to …
by the circadian clock system. Light, sensed by retina, is the predominant “zeitgeber” able to …
Understanding the significance of biological clock and its impact on cancer incidence
The circadian clock is an essential timekeeper that controls, for humans, the daily rhythm of
biochemical, physiological, and behavioral functions. Irregular performance or disruption in …
biochemical, physiological, and behavioral functions. Irregular performance or disruption in …
The time for chronotherapy in radiation oncology
L Bermúdez-Guzmán, A Blanco-Saborío… - Frontiers in …, 2021 - frontiersin.org
Five decades ago, Franz Halberg conceived the idea of a circadian-based therapy for
cancer, given the differential tolerance to treatment derived from the intrinsic host rhythms …
cancer, given the differential tolerance to treatment derived from the intrinsic host rhythms …
Period 2 suppresses the malignant cellular behaviors of colorectal cancer through the epithelial-mesenchymal transformation process
Y Xiong, Y Zhuang, M Zhong, W Qin, B Huang… - Cancer …, 2022 - journals.sagepub.com
Introduction The PER2 (Period circadian regulator 2) gene is related to the circadian clock,
and it has been deemed as a suppressor gene in osteosarcoma and lung carcinoma …
and it has been deemed as a suppressor gene in osteosarcoma and lung carcinoma …
Biological clock genes are crucial and promising biomarkers for the therapeutic targets and prognostic assessment in gastric cancer
Y Tian, Y Xie, F Bai, J Wang, D Zhang - Journal of Gastrointestinal Cancer, 2024 - Springer
Background Gastric cancer is one of the major public health problems worldwide. Circadian
rhythm disturbances driven by circadian clock genes play a role in the development of …
rhythm disturbances driven by circadian clock genes play a role in the development of …
The role of circadian gene timeless in gastrointestinal cancers
Timeless is an evolutionarily preserved protein involved in the circadian rhythm of
melanogaster flies while its role in mammalian circadian clock systems has not been fully …
melanogaster flies while its role in mammalian circadian clock systems has not been fully …
Clock genes and gastric cancer
S Cui, Y Chen, Y Guo, D Chen - Biological Rhythm Research, 2022 - Taylor & Francis
The mental, physical and behavioural changes that follow a 24-hour cycle are defined as
circadian rhythms, and this response to light and dark affects most living things, including …
circadian rhythms, and this response to light and dark affects most living things, including …