Objectives To systematically review the literature comparing the efficacy and safety of
dexmedetomidine and midazolam when used for procedural sedation. Materials and …

Dexmedetomidine (Precedex®), a pharmacologically active dextroisomer of medetomidine,
is a selective α 2-adrenergic receptor agonist. It is indicated in the US for the sedation of …

Background Dexmedetomidine has a sedative analgesic property without respiratory
depression. This study evaluated the efficacy of dexmedetomidine as an appropriate …

Background Cataract surgery is one of the most common procedures performed worldwide
in the elderly. Various medications can provide effective anesthesia and analgesia for …

Cataract surgery is predominantly performed under local/regional anesthesia, with or
without sedation. The practice pattern of sedation is unknown and seems to vary significantly …

Objective The aim of this study is to compare the sedative properties and haemodynamic
and respiratory effects of dexmedetomidine and a ketamine-propofol combination (ketofol) …

Background: Laryngeal microsurgery (LMS) causes hemodynamic instability and
postoperative agitation, cough, pain, nausea, and vomiting. Moreover, because of a short …

Methods: In a prospective study, 60 patients aged 50-70 years, scheduled for retinal surgery
under peribulbar block were divided equally to receive either MDZ: FEN or DEX 0.5 μg/kg …

This study examined the sedative effect of, and hemodynamic response to
dexmedetomidine administration in propofol-sedated swine. Sixteen swine were subjects …

Objective To evaluate whether polymorphisms in the gamma-aminobutyric acid A receptor
α1 subunit (GABRA1) gene influence sleep induction time, bispectral index score (BIS) …