Head and neck cancers are not alike when tarred with the same brush: An epigenetic perspective from the cancerization field to prognosis

D Camuzi, TA Simão, F Dias, LF Ribeiro Pinto… - Cancers, 2021 - mdpi.com
Simple Summary Squamous cell carcinomas affect different head and neck subsites and,
although these tumors arise from the same epithelial lining and share risk factors, they differ …

Inhibition of autophagy promotes the anti-tumor effect of metformin in oral squamous cell carcinoma

W Zhao, C Chen, J Zhou, X Chen, K Cai, M Shen… - Cancers, 2022 - mdpi.com
Simple Summary In this study, we found that metformin could inhibit the cell proliferation of
Oral Squamous Cell Carcinoma (OSCC) by promoting apoptosis and blocking the cell cycle …

Genome-wide DNA methylation profiling of HPV-negative leukoplakia and gingivobuccal complex cancers

M Inchanalkar, S Srivatsa, S Ambatipudi, PG Bhosale… - Clinical …, 2023 - Springer
Background Gingivobuccal complex oral squamous cell carcinoma (GBC-OSCC) is an
aggressive malignancy with high mortality often preceded by premalignant lesions …

A snapshot of miRNAs in oral squamous cell carcinoma: Difference between cancer cells and corresponding normal cells

V Hosseini, S Montazersaheb, N Hejazi… - … -Research and Practice, 2023 - Elsevier
Oral squamous cell carcinoma (OSCC) constitutes the most aggressive tumors of the oral
cavity and is one of the leading causes of cancer mortality worldwide. Although recent …

Risk factors of microscopically tumor-free surgical margins for recurrence and survival of oral squamous cell carcinoma patients

M Pei, D Han, KY Kim, DW Kim, W Nam, HJ Kim… - Frontiers in …, 2022 - frontiersin.org
Objectives The concept of adequate surgical margins remains controversial in oral
squamous cell carcinoma (OSCC) surgery. This study aimed to identify surgical margin …

TOMM34 promotes cell proliferation, migration, and invasion of OSCC and modulates mitochondrial function

Y Huang, Z Chen, X Chen, X Chen… - Journal of Oral …, 2023 - Wiley Online Library
Background 34‐kDa translocase of the outer mitochondrial membrane (TOMM34) has been
reported highly expressed in many cancers and is positively correlated to poorer prognosis …

HOXA1 3′UTR Methylation Is a Potential Prognostic Biomarker in Oral Squamous cell Carcinoma

BP Sorroche, KC Miranda, CM Beltrami, LMRB Arantes… - Cancers, 2024 - mdpi.com
Simple Summary Head and neck cancer with increased expression levels of HOXA1 tends
to have a worse outcome. This gene is regulated by DNA methylation. Herein, we studied …

Global DNA Methylation Level in Tumour and Margin Samples in Relation to Human Papilloma Virus and Epstein–Barr Virus in Patients with Oropharyngeal and Oral …

J Gaździcka, K Biernacki, K Gołąbek… - Biomedicines, 2024 - mdpi.com
Background: Aberrant DNA methylation is a common epigenetic modification in cancers,
including oropharyngeal squamous cell carcinoma (OPSCC) and oral squamous cell …

DEC1 is a potential marker of early metastasis in Oral squamous cell carcinoma

T Mao, W Chen, H Xiong, C Wang, L Yang, X Hu, K Xia… - Tissue and Cell, 2023 - Elsevier
Objective This study aimed to investigate the role of differentiated embryonic-chondrocyte
expressed gene 1 (DEC1) in early oral squamous cell carcinoma (OSCC) metastasis …

Evaluation of Proton MR Spectroscopy for the Study of the Tongue Tissue in Healthy Subjects and Patients With Tongue Squamous Cell Carcinoma: Preliminary …

S Boussida, Y François, A Heintz, Z Saidak… - Frontiers in Oral …, 2022 - frontiersin.org
Purpose To noninvasively assess spectroscopic and metabolic profiles of healthy tongue
tissue and in an exploratory objective in nontreated and treated patients with tongue …