Targeted drug delivery is emerging as a promising strategy to achieve better clinical
outcomes. Actively targeted drug delivery that utilizes overexpressed receptors or antigens …

The development of potent, specific, and pharmacologically viable chemical probes and
therapeutics is a central focus of chemical biology and therapeutic development. However, a …

Silicon photonic (SiP) sensors offer a promising platform for robust and low-cost
decentralized diagnostics due to their high scalability, low limit of detection, and ability to …

While the development of positron emission tomography (PET) radiopharmaceuticals
closely follows that of traditional drug development, there are several key considerations in …

Highlights•Combinatorial technology with DNA encoding provides synthesis and screening
of billions of new compounds.Combinatorial technology has been facilitating the synthesis …

The stabilization of peptide secondary structure via stapling is a ubiquitous goal for creating
new probes, imaging agents, and drugs. Inspired by indole‐derived crosslinks found in …

Peptide-drug conjugates (PDCs) are a class of novel molecules widely designed and
synthesized for delivering payload drugs. The peptide part plays a vital role in the whole …

The incidence of abdominal aortic aneurysms (AAAs) has substantially increased during the
last 20 years and their rupture remains the third most common cause of sudden death in the …

Following the consolidation of therapeutic proteins in the fight against cancer, autoimmune,
and neurodegenerative diseases, recent advancements in biochemistry and biotechnology …

New somatostatin analogs are highly desirable for diagnosing and treating neuroendocrine
tumors (NETs). Here we describe the solid-phase synthesis of a new octreotate (TATE) …