Long non-coding RNAs in lung cancer: Unraveling the molecular modulators of MAPK signaling

MS Hussain, O Afzal, G Gupta, ASA Altamimi… - … -Research and Practice, 2023 - Elsevier
Lung cancer (LC) continues to pose a significant global medical burden, necessitating a
comprehensive understanding of its molecular foundations to establish effective treatment …

Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy

Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …

Advancement in biopolymer assisted cancer theranostics

T Bhattacharya, S Preetam, B Ghosh… - ACS Applied Bio …, 2023 - ACS Publications
Applications of nanotechnology have increased the importance of research and
nanocarriers, which have revolutionized the method of drug delivery to treat several …

LncRNAs in non-small-cell lung cancer

L Ginn, L Shi, M La Montagna, M Garofalo - Non-coding RNA, 2020 - mdpi.com
Lung cancer is associated with a high mortality, with around 1.8 million deaths worldwide in
2018. Non-small-cell lung cancer (NSCLC) accounts for around 85% of cases and, despite …

Cancer's epigenetic drugs: where are they in the cancer medicines?

S Ghasemi - The pharmacogenomics journal, 2020 - nature.com
Epigenetic modulation can affect the characteristics of cancers. Because it is likely to
manipulate epigenetic genes, they can be considered as potential targets for cancer …

Connecting the dots: LncRNAs in the KRAS pathway and cancer

M Maqbool, MS Hussain, AS Bisht, A Kumari… - … -Research and Practice, 2024 - Elsevier
Long non-coding RNAs (lncRNAs) have been identified as important participants in several
biological functions, particularly their complex interactions with the KRAS pathway, which …

LncRNA XIST interacts with miR-454 to inhibit cells proliferation, epithelial mesenchymal transition and induces apoptosis in triple-negative breast cancer

X Li, L Hou, L Yin, S Zhao - Journal of biosciences, 2020 - Springer
Triple-negative breast cancer (TNBC) is a one of the subtypes of breast cancer which
accounts for approximately 10–20% of all breast cancers. LncRNA XIST (XIST) is reported to …

lncRNA TPTEP1 inhibits stemness and radioresistance of glioma through miR-106a-5p-mediated P38 MAPK signaling

T Tang, LX Wang, ML Yang… - Molecular medicine …, 2020 - spandidos-publications.com
Glioma is diagnosed as the most common intracranial malignant tumor. Cancer stem cells
determine stemness and radioresistance, and may facilitate glioma recurrence. The present …

Cell Cycle-Related lncRNAs as innovative targets to advance cancer management

XR Liang, YF Liu, F Chen, ZX Zhou… - Cancer Management …, 2023 - Taylor & Francis
Long non-coding RNAs (lncRNAs) are non-coding RNAs (ncRNAs) longer than 200nt. They
have complex biological functions and take part in multiple fundamental biological …

A machine learning framework that integrates multi-omics data predicts cancer-related LncRNAs

L Yuan, J Zhao, T Sun, Z Shen - BMC bioinformatics, 2021 - Springer
Abstract Background LncRNAs (Long non-coding RNAs) are a type of non-coding RNA
molecule with transcript length longer than 200 nucleotides. LncRNA has been novel …