There is no satisfactory explanation for the sex-related differences in the incidence of many
diseases and this is also true of Alzheimer's disease (AD), where females have a higher …

Introduction Socioeconomic factors and genetic predisposition are established risk factors
for dementia. It remains unclear whether associations of socioeconomic deprivation with …

Background Alzheimer's disease (AD) is a major cause of disability and mortality in older
adults. This study aimed to investigate the association of AD with education and genetic …

Introduction There is inconsistent evidence on whether genetic risk for dementia modifies
the association between hypertension and dementia. Methods In 198,965 dementia‐free …

Background Few studies using rigorous clinical diagnosis have considered whether
associations with cognitive decline are potentiated by interactions between genetic and …

There is a paucity of research regarding the association between the risk of incident
dementia and changes in smoking habits in the acute ischemic stroke population. We aimed …

Background: The detrimental impact of tobacco smoking on brain health is well recognized.
Objective: To evaluate whether smoking acts synergistically with hypertension and diabetes …

Background: Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder that is
most prevalent in elderly individuals, especially in developed countries, and its prevalence …

Dementia is recognised as a public health priority, affecting not only people living with the
syndrome but also formal and informal carers as well as society at large. The growing …

The APOE ε4 allele is the best-known genetic risk factor for developing late-onset
Alzheimer's disease. Although new evidence is emerging, the extent to which lifestyle …