One of the most prominent features of the human brain is the fabulous size of the cerebral
cortex and its intricate folding. Cortical folding takes place during embryonic development …

The developmental principles that establish the columnar edifice of the cerebral cortex
underlie its evolution and dictate its physiological operations and cognitive capacity. This …

Identifying the signals that regulate stem cell differentiation is fundamental to understanding
cellular diversity in the brain. In this paper we identify factors that act in an instructive fashion …

During development of the neocortex, the marginal zone (layer I) and the subplate (layer VII)
are the first layers to form from a primordial plexiform neoropil. The cortical plate (layers II …

The cerebral cortex, occupying over 70 percent of our brain mass, is key to any
understanding of the workings--and disorders--of the human brain. offering a …

The cerebral cortex is a striking example of an ingenious and economic design of nature.
Although the surface area of the neocortex is vastly different in the wide variety of mammals …

Progenitor cells in the cerebral cortex sequentially generate distinct classes of projection
neurons. Recent work suggests the cortex may contain intrinsically fate-restricted …

Neuroblasts produced in the ventricular zone of the neocortex migrate radially and form the
cortical plate, settling in an inside-out order. It is also well known that the tangential cell …

To gain insight into cellular and molecular mechanisms subserving neuronal cell migration
in the adult mouse forebrain, we have first investigated the cellular composition of the …

Recently, it has been shown that the early developmental organization of the archicortical
hippocampus resembles that of the neocortex. In both cortices at embryonic stages, a …