Infections and neurodegenerative diseases induce neuroinflammation, but affected
individuals often show nonneural symptoms including muscle pain and muscle fatigue. The …

Mosaic variegated aneuploidy (MVA) is a rare condition in which abnormal chromosome
counts (that is, aneuploidies), affecting different chromosomes in each cell (making it …

Members of the family Dicistroviridae are small RNA viruses containing a monopartite
positive-sense RNA genome. Dicistroviruses mainly infect arthropods, causing diseases that …

COVID-19 pandemic poses a severe threat to public health. However, so far, there are no
effective drugs for COVID-19. Transcriptomic changes and key genes related to Th2 cells in …

EGFR signaling initiates upon ligand binding which leads to activation and internalization of
the receptor-ligand complex. Here, we evaluated if BUB1 impacted EGFR signaling by …

Summary The Coronavirus Disease 2019 (COVID-19) pandemic has caused millions of
deaths and will 1 continue to exact incalculable tolls worldwide. While great strides have …

Lipophagy, the process of selective catabolism of lipid droplets (LDs) by autophagy,
maintains lipid homeostasis and provides cellular energy under metabolic adaptation, yet its …

Mitosis and endocytosis are two fundamental cellular processes essential for maintaining a
eukaryotic life. Mitosis partitions duplicated chromatin enveloped in the nuclear membrane …

Lipid droplets (LDs) are highly dynamic intracellular organelles, which are involved in lots of
biological processes. However, the dynamic morphogenesis and functions of intracellular …

BUB1 (budding uninhibited by benzimidazoles-1) is required for efficient TGF-β signaling,
through its role in stabilizing the TGFBR1 and TGFBR2 complex. Here we demonstrate that …