[HTML][HTML] Functions and dysfunctions of nitric oxide in brain

P Picón-Pagès, J Garcia-Buendia, FJ Munoz - Biochimica et Biophysica …, 2019 - Elsevier
Nitric oxide (NO) works as a retrograde neurotransmitter in synapses, allows the brain blood
flow and also has important roles in intracellular signaling in neurons from the regulation of …

The physiology and pathophysiology of nitric oxide in the brain

FX Guix, I Uribesalgo, M Coma, FJ Munoz - Progress in neurobiology, 2005 - Elsevier
Nitric oxide (NO) is a molecule with pleiotropic effects in different tissues. NO is synthesized
by NO synthases (NOS), a family with four major types: endothelial, neuronal, inducible and …

Plasticity at hippocampal to prefrontal cortex synapses: dual roles in working memory and consolidation

S Laroche, S Davis, TM Jay - Hippocampus, 2000 - Wiley Online Library
The involvement of the hippocampus and the prefrontal cortex in cognitive processes and
particularly in learning and memory has been known for a long time. However, the specific …

Local‐circuit neurones in the medial prefrontal cortex (areas 25, 32 and 24b) in the rat: morphology and quantitative distribution

PLA Gabbott, BGM Dickie, RR Vaid… - Journal of …, 1997 - Wiley Online Library
This paper is a light microscopical study describing the detailed morphology and
quantitative distribution of local circuit neurones in areas 25, 32, and 24b of the medial …

Multiple forms of short-term plasticity at excitatory synapses in rat medial prefrontal cortex

CM Hempel, KH Hartman, XJ Wang… - Journal of …, 2000 - journals.physiology.org
Short-term synaptic plasticity, in particular short-term depression and facilitation, strongly
influences neuronal activity in cerebral cortical circuits. We investigated short-term plasticity …

Modulation of synaptic plasticity in the cortex needs to understand all the players

CNJ Meunier, P Chameau, PM Fossier - Frontiers in synaptic …, 2017 - frontiersin.org
The prefrontal cortex (PFC) is involved in cognitive tasks such as working memory, decision
making, risk assessment and regulation of attention. These functions performed by the PFC …

Dual role of nitric oxide in Alzheimer's disease

A Azargoonjahromi - Nitric Oxide, 2023 - Elsevier
Nitric oxide (NO), an enzymatic product of nitric oxide synthase (NOS), has been associated
with a variety of neurological diseases such as Alzheimer's disease (AD). NO has long been …

Hesperidin pre-treatment attenuates NO-mediated cerebral ischemic reperfusion injury and memory dysfunction

V Gaur, A Kumar - Pharmacological Reports, 2010 - Springer
The present study was designed to explore the mechanism of hesperidin action via the nitric
oxide pathway in the protection against ischemic reperfusion cerebral injury-induced …

Species, strain and developmental variations in hippocampal neuronal and endothelial nitric oxide synthase clarify discrepancies in nitric oxide-dependent synaptic …

S Blackshaw, MJL Eliasson, A Sawa, CC Watkins… - Neuroscience, 2003 - Elsevier
Nitric oxide (NO) has been implicated in long-term potentiation (LTP) in pyramidal neurons
in cellular area 1 (CA1) of the hippocampus. However, considerable confusion exists about …

Recent advances on the development of NO-releasing molecules (NORMs) for biomedical applications

R Bhowmik, M Roy - European Journal of Medicinal Chemistry, 2024 - Elsevier
Nitric oxide (NO) is an important biological messenger as well as a signaling molecule that
participates in a broad range of physiological events and therapeutic applications in …