Regulation of Staphylococcus aureus Virulence

C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …

Basis of virulence in enterotoxin-mediated staphylococcal food poisoning

EL Fisher, M Otto, GYC Cheung - Frontiers in microbiology, 2018 - frontiersin.org
The Staphylococcus aureus enterotoxins are a superfamily of secreted virulence factors that
share structural and functional similarities and possess potent superantigenic activity …

The SaeRS Two-Component System of Staphylococcus aureus

Q Liu, WS Yeo, T Bae - Genes, 2016 - mdpi.com
In the Gram-positive pathogenic bacterium Staphylococcus aureus, the SaeRS two-
component system (TCS) plays a major role in controlling the production of over 20 …

Manipulation of innate and adaptive immunity by staphylococcal superantigens

SW Tuffs, SMM Haeryfar, JK McCormick - Pathogens, 2018 - mdpi.com
Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by
Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link …

A genetic regulatory see-saw of biofilm and virulence in MRSA pathogenesis

H Patel, S Rawat - Frontiers in microbiology, 2023 - frontiersin.org
Staphylococcus aureus is one of the most common opportunistic human pathogens causing
several infectious diseases. Ever since the emergence of the first methicillin-resistant …

Stress-induced inactivation of the Staphylococcus aureus purine biosynthesis repressor leads to hypervirulence

MI Goncheva, RS Flannagan, BE Sterling… - Nature …, 2019 - nature.com
Staphylococcus aureus is a significant cause of human infection. Here, we demonstrate that
mutations in the transcriptional repressor of purine biosynthesis, purR, enhance the …

Impact of Currently Marketed Tampons and Menstrual Cups on Staphylococcus aureus Growth and Toxic Shock Syndrome Toxin 1 Production In Vitro

L Nonfoux, M Chiaruzzi, C Badiou… - Applied and …, 2018 - Am Soc Microbiol
Fifteen currently marketed intravaginal protection products (11 types of tampon and 4 types
of menstrual cup) were tested by the modified tampon sac method to determine their effect …

Superantigens, a paradox of the immune response

S Noli Truant, DM Redolfi, MB Sarratea, EL Malchiodi… - Toxins, 2022 - mdpi.com
Staphylococcal enterotoxins are a wide family of bacterial exotoxins with the capacity to
activate as much as 20% of the host T cells, which is why they were called superantigens …

[HTML][HTML] Clinical and molecular epidemiology of staphylococcal toxic shock syndrome in the United Kingdom

H Sharma, D Smith, CE Turner, L Game… - Emerging Infectious …, 2018 - ncbi.nlm.nih.gov
Staphylococcal toxic shock syndrome (TSS) was originally described in menstruating
women and linked to TSS toxin 1 (TSST-1)–producing Staphylococcus aureus. Using UK …

Redox-Sensing Under Hypochlorite Stress and Infection Conditions by the Rrf2-Family Repressor HypR in Staphylococcus aureus

VV Loi, T Busche, K Tedin, J Bernhardt… - Antioxidants & redox …, 2018 - liebertpub.com
Aims: Staphylococcus aureus is a major human pathogen and has to cope with reactive
oxygen and chlorine species (ROS, RCS) during infections, which requires efficient …