Identification and management of potentially premalignant oral epithelial lesions (PPOELs)
at highest risk of malignant transformation holds great promise for successful secondary …

Approximately 15% of cancers are attributable to the inflammatory process, and growing
evidence supports an association between oral squamous cell carcinoma (OSCC) and …

Objective The aim of this study was to clarify the role of IL-33 in tumor progression. Methods
Surgical specimens from 81 patients with squamous cell carcinoma of the tongue were …

Although mast cells (MCs) have been discovered over 130 years ago, their function was
almost exclusively linked to allergic affections. At the time being, it is well known that MCs …

According to literature data, potentially premalignant oral lesions are the basis of over 85%
of cell carcinomas. Despite multiple advances achieved during the last few decades in the …

Oral potentially malignant disorders (OPMD) develop in a complex tissue microenvironment
where they grow sustainably, acquiring oral squamous cell carcinoma (OSCC) …

The worldwide annual incidence of oral squamous cell carcinoma (OSCC) is over 300,000
cases with a mortality rate of 48%. This cancer type accounts for 90% of all oral cancers, with …

Background Aim of the study was to assess the role of angiogenesis in the process of
malignant transformation of clinical diagnosed oral leucoplakia (OL). Materials and methods …

Mast cell (MC) active mediators promote inflammation through changes induced in the
connective tissue components of human gingiva. The aim of this study was to evaluate the …

Oral potentially malignant disorders (OPMDs) are chronic inflammatory diseases in which
cells suffer hypoxia referring to deprivation of adequate oxygen supply. Hyperbaric oxygen …