Asthma | From Bronchoconstriction to Airways Inflammation and Remodeling | American
Journal of Respiratory and Critical Care Medicine ATS Journals Logo Official Publications …

COPD is an obstructive airway disorder characterized by a slowly progressive and
irreversible decrease in FEV1 (1, 2, 7). FEV1 decreases are caused by a narrowing of …

Eosinophil-derived TGF-β has been implicated in remodeling events in asthma. We
hypothesized that reduction of bronchial mucosal eosinophils with anti–IL-5 would reduce …

With mathematical and computational models furthering our understanding of lung
mechanics, function and disease, this book provides an all-inclusive introduction to the topic …

METHODS The left or right lungs of cadavers coming to Coroner's autopsy within the
metropolitan area of Perth, Western Australia, were obtained if the cause of death was …

Background Severe steroid-insensitive asthma is a substantial clinical problem. Effective
treatments are urgently required, however, their development is hampered by a lack of …

This study was designed to examine the inflammatory process in the central and peripheral
airways of surgically resected lungs from asthmatic and nonasthmatic subjects. Lung …

Edema occurs in asthma and other inflammatory diseases when the rate of plasma leakage
from blood vessels exceeds the drainage through lymphatic vessels and other routes. It is …

Continuing Medical Education examination CONTINUING MEDICAL EDUCATION
ARTICLECredit can now be obtained, free for a limited time, by reading the following review …

Airway wall remodeling is an established pathological feature in asthma. Its causes are not
well understood, but one mediator of potential relevance is transforming growth factor-beta 1 …