There has been recent renewed interest in studying human early embryonic development.
The advent of improved culture conditions to maintain blastocysts in vitro for an extended …

The tarsal glands of Meibom (glandulae tarsales) are large sebaceous glands located in the
eyelids and, unlike those of the skin, are unassociated with hairs. According to Duke-Elder …

The regulated migration of cells is essential for development and tissue homeostasis, and
aberrant cell migration can lead to an impaired immune response and the progression of …

Abstract Specification of germ cell fate is fundamental in development and heredity. Recent
evidence indicates that in mice, specification of primordial germ cells (PGCs), the common …

Transitions in cell states are controlled by combinatorial actions of transcription factors.
BLIMP1, the key regulator of primordial germ cell (PGC) specification, apparently acts …

Specification of germ cell fate is fundamental in development. With a highly representative
single-cell microarray and rigorous quantitative PCR analysis, we defined the genome-wide …

Azoospermia due to obstructive and non-obstructive mechanisms is a common
manifestation of male infertility accounting for 10-15% of such cases. Known genetic factors …

Germ cell fate in mice is induced in proximal epiblast cells at Embryonic Day (E) 6.5 by
signaling molecules. Prdm1 (also known as Blimp1)-positive lineage-restricted precursors of …

Rotavirus is a major cause of diarrhea worldwide and exhibits a pronounced small intestinal
epithelial cell (IEC) tropism. Both human infants and neonatal mice are highly susceptible …

After Ag activation of naive T cells in vitro, extensive growth and differentiation into effector
cells depend upon IL-2. DNA microarray analysis was used to identify IL-2-dependent …