Since the first dendrimer was reported in 1978 by Fritz Vögtle, dendrimer research has
grown exponentially, from synthesis to application in the past four decades. The distinct …

ABSTRACT A commonly held view is that nanocarriers conjugated to polyethylene glycol
(PEG) are non-immunogenic. However, many studies have reported that unexpected …

Liposome as a revolutionizing carrier, has exhibited favorable aspects in drug delivery.
However, there are numerous challenges affecting its effectiveness. Hypersensitivity …

Functionalized graphene oxide (GO) and reduced GO (rGO) based nanomaterials hold a
great potential for cancer photothermal therapy. However, their systemic administration has …

Liposomes, vesicles composed of a phospholipid bilayer, are considered a remarkably
advanced drug delivery system due to their unique properties, including their …

Cardiovascular disease is one of the major contributors to global disease burden.
Atherosclerosis is an inflammatory process that involves the accumulation of lipids and …

Highlights•Oral route of administration is the preferred route for drug delivery.•Dosage form
designing plays an essential role in oral peptide delivery.•Preclinical and clinical aspects of …

Polyethylene glycol (PEG) is continuing to be a star molecular to increase hydrophilicity and
to lengthen the blood circulation after conjugation with therapeutic proteins, nucleotides and …

Drug encapsulated liposomes and monoclonal antibodies (Mabs) are two distinctively
different classes of therapeutics, but both aim to become the ultimate “magic bullet”. While …

Gene therapy through the use of siRNA and a polymeric carrier are becoming an efficient
therapeutic option to conventional pharmaceutical formulations for the treatment of deadly …