Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii

M Hamidian, SJ Nigro - Microbial genomics, 2019 - microbiologyresearch.org
Acinetobacter baumannii is a nosocomial pathogen that has emerged as a global threat
because of high levels of resistance to many antibiotics, particularly those considered to be …

OXA β-lactamases

BA Evans, SGB Amyes - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The OXA β-lactamases were among the earliest β-lactamases detected; however, these
molecular class D β-lactamases were originally relatively rare and always plasmid …

Mobile genetic elements in Acinetobacter antibiotic‐resistance acquisition and dissemination

HR Noel, JR Petrey, LD Palmer - … of the New York Academy of …, 2022 - Wiley Online Library
Pathogenic Acinetobacter species, most notably Acinetobacter baumannii, are a significant
cause of healthcare‐associated infections worldwide. Acinetobacter infections are of …

Blue-carba, an easy biochemical test for detection of diverse carbapenemase producers directly from bacterial cultures

J Pires, A Novais, L Peixe - Journal of clinical microbiology, 2013 - Am Soc Microbiol
Quick, simple, and reliable methods are needed for laboratory detection of carbapenemases
that are widely disseminated among Gram-negative bacteria, in order to improve the …

Plasmid-Mediated Antibiotic Resistance and Virulence in Gram-Negatives: the Klebsiella pneumoniae Paradigm

MS Ramirez, GM Traglia, DL Lin, T Tran… - Microbiology …, 2014 - Am Soc Microbiol
Plasmids harbor genes coding for specific functions including virulence factors and antibiotic
resistance that permit bacteria to survive the hostile environment found in the host and resist …

Structure and Evolution of Acinetobacter baumannii Plasmids

AD Salgado-Camargo, S Castro-Jaimes… - Frontiers in …, 2020 - frontiersin.org
Acinetobacter baumannii is an emergent bacterial pathogen that provokes many types of
infections in hospitals around the world. The genome of this organism consists of a …

Antimicrobial resistance in Romania: updates on gram-negative ESCAPE pathogens in the clinical, veterinary, and aquatic sectors

IC Barbu, I Gheorghe-Barbu, GA Grigore… - International Journal of …, 2023 - mdpi.com
Multidrug-resistant Gram-negative bacteria such as Acinetobacter baumannii,
Pseudomonas aeruginosa, and members of the Enterobacterales order are a challenging …

Insights on the Horizontal Gene Transfer of Carbapenemase Determinants in the Opportunistic Pathogen Acinetobacter baumannii

GJ Da Silva, S Domingues - Microorganisms, 2016 - mdpi.com
Horizontal gene transfer (HGT) is a driving force to the evolution of bacteria. The fast
emergence of antimicrobial resistance reflects the ability of genetic adaptation of pathogens …

Class D β-lactamases

EJ Yoon, SH Jeong - Journal of Antimicrobial Chemotherapy, 2021 - academic.oup.com
Class D β-lactamases are composed of 14 families and the majority of the member enzymes
are included in the OXA family. The genes for class D β-lactamases are frequently identified …

Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and …

HY Ou, SN Kuang, X He, BM Molgora, PJ Ewing… - Scientific reports, 2015 - nature.com
Acinetobacter baumannii is an important human pathogen due to its multi-drug resistance. In
this study, the genome of an ST10 outbreak A. baumannii isolate LAC-4 was completely …