Mass spectrometry-based protein footprinting for higher-order structure analysis: fundamentals and applications
Proteins adopt different higher-order structures (HOS) to enable their unique biological
functions. Understanding the complexities of protein higher-order structures and dynamics …
functions. Understanding the complexities of protein higher-order structures and dynamics …
Covalent labeling-mass spectrometry with non-specific reagents for studying protein structure and interactions
Using mass spectrometry (MS) to obtain information about a higher order structure of protein
requires that a protein's structural properties are encoded into the mass of that protein …
requires that a protein's structural properties are encoded into the mass of that protein …
Mass spectrometry methods for studying structure and dynamics of biological macromolecules
L Konermann, S Vahidi, MA Sowole - Analytical chemistry, 2014 - ACS Publications
All processes that occur within living organisms are intimately linked to biological
macromolecules such as proteins, nucleic acids, or polysaccharides. Phospholipid …
macromolecules such as proteins, nucleic acids, or polysaccharides. Phospholipid …
Laser‐initiated radical trifluoromethylation of peptides and proteins: Application to mass‐spectrometry‐based protein footprinting
Described is a novel, laser‐initiated radical trifluoromethylation for protein footprinting and
its broad residue coverage.. CF3 reacts with 18 of the 20 common amino acids, including …
its broad residue coverage.. CF3 reacts with 18 of the 20 common amino acids, including …
Evidence for OH radical production during electrocatalysis of oxygen reduction on Pt surfaces: consequences and application
JM Noël, A Latus, C Lagrost, E Volanschi… - Journal of the …, 2012 - ACS Publications
Multielectronic O2 reduction reactions (ORR) at Pt surface (and at Au surface for comparison
purpose) were examined both in water and in organic solvents using a strategy based on …
purpose) were examined both in water and in organic solvents using a strategy based on …
The Application of Fluorine‐Containing Reagents in Structural Proteomics
Structural proteomics refers to large‐scale mapping of protein structures in order to
understand the relationship between protein sequence, structure, and function. Chemical …
understand the relationship between protein sequence, structure, and function. Chemical …
Release of free amino acids upon oxidation of peptides and proteins by hydroxyl radicals
Hydroxyl radical-induced oxidation of proteins and peptides can lead to the cleavage of the
peptide, leading to a release of fragments. Here, we used high-performance liquid …
peptide, leading to a release of fragments. Here, we used high-performance liquid …
Probing the time scale of FPOP (fast photochemical oxidation of proteins): radical reactions extend over tens of milliseconds
S Vahidi, L Konermann - Journal of The American Society for Mass …, 2016 - ACS Publications
Hydroxyl radical (⋅ OH) labeling with mass spectrometry detection reports on protein
conformations and interactions. Fast photochemical oxidation of proteins (FPOP) involves⋅ …
conformations and interactions. Fast photochemical oxidation of proteins (FPOP) involves⋅ …
Development of a microflow system for in-cell footprinting coupled with mass spectrometry
Fast photochemical oxidation of proteins (FPOP) has become a valuable tool for protein
structural characterization. The method has recently been demonstrated to oxidatively …
structural characterization. The method has recently been demonstrated to oxidatively …
Dynamics of hydrogen nanobubbles in KLH protein solution studied with in situ wet-TEM
Although the stability of the nanobubble remains a controversial issue that is subject to the
classical predictions of high Laplace pressure, we demonstrate that a hydrogen nanobubble …
classical predictions of high Laplace pressure, we demonstrate that a hydrogen nanobubble …