Mfd Protein and Transcription–Repair Coupling in Escherichia coli

CP Selby - Photochemistry and photobiology, 2017 - Wiley Online Library
Abstract In 1989, transcription–repair coupling (TRC) was first described in Escherichia coli,
as the transcription‐dependent, preferential nucleotide excision repair (NER) of UV …

Light-Triggered Carotenogenesis in Myxococcus xanthus: New Paradigms in Photosensory Signaling, Transduction and Gene Regulation

S Padmanabhan, AJ Monera-Girona, R Pérez-Castaño… - Microorganisms, 2021 - mdpi.com
Myxobacteria are Gram-negative δ-proteobacteria found predominantly in terrestrial habitats
and often brightly colored due to the biosynthesis of carotenoids. Carotenoids are lipophilic …

Understanding molecular consequences of putative drug resistant mutations in Mycobacterium tuberculosis

S Portelli, JE Phelan, DB Ascher, TG Clark… - Scientific reports, 2018 - nature.com
Genomic studies of Mycobacterium tuberculosis bacteria have revealed loci associated with
resistance to anti-tuberculosis drugs. However, the molecular consequences of …

Assessment of unconventional antimicrobial compounds for the control of 'Candidatus Liberibacter asiaticus', the causative agent of citrus greening disease

CL Gardner, DR da Silva, FA Pagliai, L Pan… - Scientific reports, 2020 - nature.com
In this study, newly identified small molecules were examined for efficacy against
'Candidatus Liberibacter asiaticus' in commercial groves of sweet orange (Citrus sinensis) …

Multifactorial control of the expression of a CRISPR-Cas system by an extracytoplasmic function σ/anti-σ pair and a global regulatory complex

D Bernal-Bernal, J Abellon-Ruiz, AA Iniesta… - Nucleic Acids …, 2018 - academic.oup.com
Expression of CRISPR-Cas systems is a prerequisite for their defensive role against
invading genetic elements. Yet, much remains unknown about how this crucial step is …

House of CarDs: Functional insights into the transcriptional regulator CdnL

EL Smith, ED Goley - Molecular Microbiology, 2024 - Wiley Online Library
Regulation of bacterial transcription is a complex and multi‐faceted phenomenon that is
critical for growth and adaptation. Proteins in the CarD_CdnL_TRCF family are widespread …

Proteomic Signatures of Microbial Adaptation to the Highest Ultraviolet-Irradiation on Earth: Lessons From a Soil Actinobacterium

F Zannier, LR Portero, T Douki, W Gärtner… - Frontiers in …, 2022 - frontiersin.org
In the Central Andean region in South America, high-altitude ecosystems (3500–6000 masl)
are distributed across Argentina, Chile, Bolivia, and Peru, in which poly-extremophilic …

Caulobacter crescentus CdnL is a non-essential RNA polymerase-binding protein whose depletion impairs normal growth and rRNA transcription

A Gallego-García, AA Iniesta, D González, J Collier… - Scientific reports, 2017 - nature.com
CdnL is an essential RNA polymerase (RNAP)-binding activator of rRNA transcription in
mycobacteria and myxobacteria but reportedly not in Bacillus. Whether its function and …

Identification of the Tolfenamic Acid Binding Pocket in PrbP from Liberibacter asiaticus

L Pan, CL Gardner, FA Pagliai, CF Gonzalez… - Frontiers in …, 2017 - frontiersin.org
In Liberibacter asiaticus, PrbP is an important transcriptional accessory protein that was
found to regulate gene expression through interactions with the RNA polymerase β-subunit …

Structure-guided designing and evaluation of peptides targeting bacterial transcription

G Kaur, S Kapoor, S Kaundal, D Dutta… - … in bioengineering and …, 2020 - frontiersin.org
The mycobacterial RNA polymerase (RNAP) is an essential and validated drug target for
developing antibacterial drugs. The β-subunit of Mycobacterium tuberculosis (Mtb) RNAP …