[HTML][HTML] Beyond activation: characterizing microglial functional phenotypes

J Lier, WJ Streit, I Bechmann - Cells, 2021 - mdpi.com
Classically, the following three morphological states of microglia have been defined:
ramified, amoeboid and phagocytic. While ramified cells were long regarded as “resting” …

Immune mechanisms in inflammatory anemia

SP Canny, SL Orozco, NK Thulin… - Annual review of …, 2023 - annualreviews.org
Maintaining the correct number of healthy red blood cells (RBCs) is critical for proper
oxygenation of tissues throughout the body. Therefore, RBC homeostasis is a tightly …

Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing

Y Jiang, AA Trotsyuk, S Niu, D Henn, K Chen… - Nature …, 2023 - nature.com
Abstract 'Smart'bandages based on multimodal wearable devices could enable real-time
physiological monitoring and active intervention to promote healing of chronic wounds …

Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells

J Yang, M Vamvini, P Nigro, LL Ho, K Galani, M Alvarez… - Cell metabolism, 2022 - cell.com
Exercise training is critical for the prevention and treatment of obesity, but its underlying
mechanisms remain incompletely understood given the challenge of profiling …

A single-cell atlas of non-haematopoietic cells in human lymph nodes and lymphoma reveals a landscape of stromal remodelling

Y Abe, M Sakata-Yanagimoto, M Fujisawa… - Nature cell …, 2022 - nature.com
The activities of non-haematopoietic cells (NHCs), including mesenchymal stromal cells and
endothelial cells, in lymphomas are reported to underlie lymphomagenesis. However, our …

Context-aware deconvolution of cell–cell communication with Tensor-cell2cell

E Armingol, HM Baghdassarian, C Martino… - Nature …, 2022 - nature.com
Cell interactions determine phenotypes, and intercellular communication is shaped by
cellular contexts such as disease state, organismal life stage, and tissue microenvironment …

Endothelial sensing of AHR ligands regulates intestinal homeostasis

BG Wiggins, YF Wang, A Burke, N Grunberg… - Nature, 2023 - nature.com
Endothelial cells line the blood and lymphatic vasculature, and act as an essential physical
barrier, control nutrient transport, facilitate tissue immunosurveillance and coordinate …

SPASCER: spatial transcriptomics annotation at single-cell resolution

Z Fan, Y Luo, H Lu, T Wang, YZ Feng… - Nucleic Acids …, 2023 - academic.oup.com
In recent years, the explosive growth of spatial technologies has enabled the
characterization of spatial heterogeneity of tissue architectures. Compared to traditional …

Unraveling the molecular architecture of autoimmune thyroid diseases at spatial resolution

R Martínez-Hernández, N Sánchez de la Blanca… - Nature …, 2024 - nature.com
Autoimmune thyroid diseases (AITD) such as Graves' disease (GD) or Hashimoto's
thyroiditis (HT) are organ-specific diseases that involve complex interactions between …

Long-term anti-tumor effects following both conventional radiotherapy and FLASH in fully immunocompetent animals with glioblastoma

E Liljedahl, E Konradsson, E Gustafsson… - Scientific Reports, 2022 - nature.com
Radiotherapy can induce an immunological response. One limiting factor is side effects on
normal tissue. Using FLASH radiotherapy, side effects could possibly be reduced. The …