Highlights•A bibliometric review of drug repurposing provides novel insights into the
practice.•Some drugs have been tried in hundreds of diseases.•Even an old drug like …

In recent years the amount of experimental data that is produced in biomedical research and
the number of papers that are being published in this field have grown rapidly. In order to …

The immense growth of MEDLINE coupled with the realization that a vast amount of
biomedical knowledge is recorded in free-text format, has led to the appearance of a large …

High-throughput screening (HTS) assays that measure the in vitro toxicity of environmental
compounds have been widely applied as an alternative to in vivo animal tests of chemical …

The conventional drug discovery pipeline has proven to be unsustainable for rare diseases.
Herein, we discuss recent advances in biomedical knowledge mining applied to discovering …

The rapid increase in the flow rate of published digital information in all disciplines has
resulted in a pressing need for techniques that can simplify the use of this information. The …

Developing a drug de novo is a laborious and costly endeavor. Thus, the repositioning of
already approved drugs for the treatment of new diseases is promising and valuable. One …

The vast nature of scientific publications brings out the importance of Literature-Based
Discovery (LBD) research that is highly beneficial to accelerate knowledge acquisition and …

Vascular development is a complex process regulated by dynamic biological networks that
vary in topology and state across different tissues and developmental stages. Signals …

Edited by world-famous pioneers in chemoinformatics, this is a clearly structured and
applications-oriented approach to the topic, providing up-to-date and focused information on …