Sex-and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities

X Zhang, H Zhong, Y Li, Z Shi, H Ren, Z Zhang, X Zhou… - Nature Aging, 2021 - nature.com
Lifelong sex-and age-related trajectories of the human gut microbiota remain largely
unexplored. Using metagenomics, we derived the gut microbial composition of 2,338 adults …

Effect of caloric restriction on BMI, gut microbiota, and blood amino acid levels in non-obese adults

H Zou, D Wang, H Ren, K Cai, P Chen, C Fang, Z Shi… - Nutrients, 2020 - mdpi.com
Adequate calorie restriction (CR) as a healthy lifestyle is recommended not only for people
with metabolic disorders but also for healthy adults. Previous studies have mainly focused …

A population-based study of precision health assessments using multi-omics network-derived biological functional modules

W Zhang, Z Wan, X Li, R Li, L Luo, Z Song, Y Miao… - Cell Reports …, 2022 - cell.com
Recent technological advances in multi-omics and bioinformatics provide an opportunity to
develop precision health assessments, which require big data and relevant bioinformatic …

Model organism life extending therapeutics modulate diverse nodes in the drug-gene-microbe tripartite human longevity interactome

R Salekeen, MS Lustgarten, U Khan… - Journal of Biomolecular …, 2024 - Taylor & Francis
Advances in antiaging drug/lead discovery in animal models constitute a large body of
literature on novel senotherapeutics and geroprotectives. However, with little direct evidence …

M-GWAS for the gut microbiome in Chinese adults illuminates on complex diseases

X Liu, S Tang, H Zhong, X Tong, Z Jie, Q Ding, D Wang… - bioRxiv, 2019 - biorxiv.org
The gut microbiome has been established as a key environmental factor to health. Genetic
influences on the gut microbiome have been reported, yet, doubts remain as to the …

Inter-determination of blood metabolite levels and gut microbiome supported by Mendelian randomization

X Liu, X Tong, Y Zou, X Lin, H Zhao, L Tian, Z Jie… - bioRxiv, 2020 - biorxiv.org
The gut microbiome has been implicated in a variety of physiological states. Controversy
over causality, however, has always haunted microbiome studies. Here, we utilized the …

Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample

S Jain - US Patent 10,837,046, 2020 - Google Patents
Disclosed herein are methods of extracting genetic material from a diverse population of one
or more types of microbes in a sample. Microbes can be prokaryotes or eukaryotes and may …

Calorie restriction intervention induces enterotype-associated BMI loss in nonobese individuals

H Zou, D Wang, H Ren, P Chen, C Fang, Z Shi… - bioRxiv, 2019 - biorxiv.org
Calorie restriction (CR), which has the potential effect to weight loss and blood amino acids,
has been demonstrated to associate with gut microbiota in human, especially in obese …

Universal method for extracting nucleic acid molecules from a diverse population of one or more types of microbes in a sample

S Jain - US Patent 11,959,125, 2024 - Google Patents
Disclosed herein are methods of extracting genetic material from a diverse population of one
or more types of microbes in a sample. Microbes can be prokaryotes or eukaryotes and may …