Body sodium (Na) levels must be maintained within a narrow range for the correct
functioning of the organism (Na homeostasis). Na disorders include not only elevated levels …

Puberty is a complex process leading to physical, sexual, and psychosocial maturation. The
changes in morphology and organ function during puberty also affect blood pressure (BP) …

Thirst plays a vital role in the regulation of body fluid homeostasis and if deregulated can be
life-threatening. Interoceptive neurons in the subfornical organ (SFO) are intrinsically …

Alzheimer's disease (AD), the most prevalent form of dementia, is expected to rise
dramatically in incidence due to the global population aging. Traditional diagnostic …

Thirst and salt appetite are temporarily suppressed after water and salt ingestion,
respectively, before absorption; however, the underlying neural mechanisms remain …

Hyponatremia on admission has been related to worse outcomes in patients with COVID-19
infection. However, little is known about the frequency and the associated risk factors of …

Maintaining internal osmolality constancy is essential for life. Release of arginine
vasopressin (AVP) in response to hyperosmolality is critical. Current hypotheses for …

The Scn7A gene encodes NaX, an atypical noninactivating Na+ channel, whose expression
in sensory circumventricular organs is essential to maintain homeostatic responses for body …

Thirst and water intake are regulated by the organum vasculosum of the lamina terminalis
(OVLT) and subfornical organ (SFO), located around the anteroventral third ventricle, which …

We aimed to investigate the associations of hypo-and hyperosmolarity at hospital admission
with clinical characteristics and outcomes in 5645 consecutive hospitalized COVID-19 …