Obesity is associated with an increased risk of developing insulin resistance and type 2
diabetes. In obese individuals, adipose tissue releases increased amounts of non-esterified …

Over the last decade, an abundance of evidence has emerged demonstrating a close link
between metabolism and immunity. It is now clear that obesity is associated with a state of …

Psoriasis is now classified as an immune-mediated inflammatory disease (IMID) of the skin.
It is being recognized that patients with various IMIDs, including psoriasis, are at higher risk …

It now appears that, in most obese patients, obesity is associated with a low-grade
inflammation of white adipose tissue (WAT) resulting from chronic activation of the innate …

Obesity is an energy‐rich condition associated with overnutrition, which impairs systemic
metabolic homeostasis and elicits stress. It also activates an inflammatory process in …

Obesity-associated insulin resistance is a major risk factor for type 2 diabetes and
cardiovascular disease. In the past decade, a large number of endocrine, inflammatory …

Compelling evidence supports the concepts that gut microbiota actively promotes weight
gain and fat accumulation and sustains, indirectly, a condition of low-grade inflammation …

White adipose tissue was believed to be just an energy-storage organ, but it is now
recognized to be an active participant in energy homoeostasis and physiological functions …

Interleukin (IL)-6 is one of several proinflammatory cytokines that have been associated with
insulin resistance and type 2 diabetes. A two-to threefold elevation of circulating IL-6 has …

Interleukin (IL)-6-type cytokines are critically involved in health and disease. The duration
and strength of IL-6-type cytokine-mediated signaling is tightly regulated to avoid …