Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of
cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and …

Limbal stem cells constitute an important cell population required for regeneration of the
corneal epithelium. If insults to limbal stem cells or their niche are sufficiently severe, a …

Limbal stem cell deficiency (LSCD) is characterized by the loss of limbal epithelial stem cells
(LESCs) which compromises corneal transparency, leading to blindness. It cannot be …

Each day, about 2000 US workers have a job-related eye injury requiring medical treatment.
Corneal diseases are the fifth cause of blindness worldwide. Most of these diseases can be …

Limbal stem cell deficiency and corneal disorders are among the top global threats for
human vision. Emerging therapies that integrate stem cell transplantation with engineered …

Any significant loss of vision or blindness caused by corneal damages is referred to as
corneal blindness. Corneal blindness is the fourth most common cause of blindness …

Keeping the integrity and transparency of the cornea is the most important issue to ensure
normal vision. There are more than 10 million patients going blind due to the cornea …

The use of amniotic membrane (AM) in ophthalmology has been increasing in recent years
due to its multiple biological and tectonic properties, improvement in the process of …

Purpose Animal models are pivotal for elucidating pathophysiological mechanisms and
evaluating novel therapies. This systematic review identified studies that developed or …

The potential of personalised genome editing reaching the clinic has come to light due to
advancements in the field of gene editing, namely the development of CRISPR/Cas9. The …