Phenylpropynones as Selective Disulfide Rebridging Bioconjugation Reagents
D Maes, M Nicque, M Iftikhar, JM Winne - Organic Letters, 2024 - ACS Publications
Simple 1-phenylpropynones undergo a selective double thia-Michael addition with thiols in
buffered media, yielding an interesting dithioacetal linkage joining two thiols. The reactivity …
buffered media, yielding an interesting dithioacetal linkage joining two thiols. The reactivity …
[HTML][HTML] Hetero-Diels–Alder and CuAAC Click Reactions for Fluorine-18 Labeling of Peptides: Automation and Comparative Study of the Two Methods
T Maujean, SM Ramanoudjame, S Riché, C Le Guen… - Molecules, 2024 - mdpi.com
Radiolabeled peptides are valuable tools for diagnosis or therapies; they are often
radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we …
radiofluorinated using an indirect approach based on an F-18 prosthetic group. Herein, we …
[HTML][HTML] Exploring macrocyclization strategies to design novel octreotate-based radioconjugates
D Chapeau, A Iroidis, S Beckman, Y Seimbille - Tetrahedron Letters, 2024 - Elsevier
Peptides derived from the cyclic tetradecapeptide somastostatin exhibit a strong affinity
primarily towards the G-protein coupled somatostatin receptor subtype 2 (SSTR2), which is …
primarily towards the G-protein coupled somatostatin receptor subtype 2 (SSTR2), which is …