[HTML][HTML] Bone fracture healing in mechanobiological modeling: A review of principles and methods
Bone fracture is a very common body injury. The healing process is physiologically complex,
involving both biological and mechanical aspects. Following a fracture, cell migration …
involving both biological and mechanical aspects. Following a fracture, cell migration …
Microcomputed tomography: approaches and applications in bioengineering
JD Boerckel, DE Mason, AM McDermott… - Stem cell research & …, 2014 - Springer
Microcomputed tomography (microCT) has become a standard and essential tool for
quantifying structure-function relationships, disease progression, and regeneration in …
quantifying structure-function relationships, disease progression, and regeneration in …
The application of pulsed electromagnetic fields (PEMFs) for bone fracture repair: past and perspective findings
Bone fractures are one of the most commonly occurring injuries of the musculoskeletal
system. A highly complex physiological process, fracture healing has been studied …
system. A highly complex physiological process, fracture healing has been studied …
Mechano-biological computer model of scaffold-supported bone regeneration: effect of bone graft and scaffold structure on large bone defect tissue patterning
Large segmental bone defects represent a clinical challenge for which current treatment
procedures have many drawbacks. 3D-printed scaffolds may help to support healing, but …
procedures have many drawbacks. 3D-printed scaffolds may help to support healing, but …
Bone: an outstanding composite material
Bone is an outstanding, well-designed composite. It is constituted by a multi-level structure
wherein its properties and behavior are dependent on its composition and structural …
wherein its properties and behavior are dependent on its composition and structural …
Recent advances in mechanobiological modeling of bone regeneration
H Isaksson - Mechanics Research Communications, 2012 - Elsevier
Skeletal regeneration and bone fracture repair involves complex cellular and molecular
events that result in new bone formation. Many of the critical steps during bone healing are …
events that result in new bone formation. Many of the critical steps during bone healing are …
Intramedullary nailing biomechanics: evolution and challenges
N Rosa, M Marta, M Vaz, SMO Tavares… - Proceedings of the …, 2019 - journals.sagepub.com
This article aims to review the biomechanical evolution of intramedullary nailing and
describe the breakthrough concepts which allowed for nail improvement and its current …
describe the breakthrough concepts which allowed for nail improvement and its current …
PCL strut-like scaffolds appear superior to gyroid in terms of bone regeneration within a long bone large defect: An in silico study
The treatment of large bone defects represents a major clinical challenge. 3D printed
scaffolds appear as a promising strategy to support bone defect regeneration. The 3D …
scaffolds appear as a promising strategy to support bone defect regeneration. The 3D …
[HTML][HTML] Role of mathematical modeling in bone fracture healing
P Pivonka, CR Dunstan - BoneKEy reports, 2012 - ncbi.nlm.nih.gov
Bone fracture healing is a complex physiological process commonly described by a four-
phase model consisting of an inflammatory phase, two repair phases with soft callus …
phase model consisting of an inflammatory phase, two repair phases with soft callus …
Degradation of extracellular matrix regulates osteoblast migration: A microfluidic-based study
N Movilla, C Borau, C Valero, JM García-Aznar - Bone, 2018 - Elsevier
Bone regeneration is strongly dependent on the capacity of cells to move in a 3D
microenvironment, where a large cascade of signals is activated. To improve the …
microenvironment, where a large cascade of signals is activated. To improve the …