Nowadays, one of the leading causes of death in humans is cancer, which is still on the rise
globally and is in great need of intense study on the pathogenic mechanism and effective …

The reduction in androgen synthesis and the blockade of the androgen receptor (AR)
function by chemical castration and AR signaling inhibitors represent the main treatment …

Recurring sequences of genomic alterations occurring across patients can highlight
repeated evolutionary processes with significant implications for predicting cancer …

Reprogramming of methionine metabolism is a conserved hallmark of tumorigenesis.
Recent studies have revealed mechanisms regulating methionine metabolism within the …

Sharply increased reactive oxygen species (ROS) are thought to induce oxidative stress,
damage cell structure and cause cell death; however, its role in prostate cancer remains …

Histone methylation can affect chromosome structure and binding to other proteins,
depending on the type of amino acid being modified and the number of methyl groups …

A high number of cancer-related deaths (up to 90) are due to metastasis and simple
definition of metastasis is new colony formation of tumor cells in a secondary site. In tumor …

The escalating global cancer burden underscores the urgent need for more effective
therapeutic strategies. Phytochemicals, naturally occurring compounds in plants, have …

Metastatic prostate cancer (PCa) poses a significant therapeutic challenge with high
mortality rates. Utilizing CRISPR-Cas9 in vivo, we target five potential tumor suppressor …

Simple Summary The incidence of prostate cancer is rising, primarily due to its prevalence
among elderly men, and with increased life expectancy, these numbers are expected to …