Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Background Every year, at least one million children become ill with tuberculosis and
around 200,000 children die. Xpert MTB/RIF and Xpert Ultra are World Health Organization …

The objectives of the 2022 consolidated guidelines are: to provide policy makers and
implementing partners with evidence-based recommendations on the cascade of care for …

Objectives The WHO currently recommends stool testing using GeneXpert MTB/Rif (Xpert)
for the diagnosis of paediatric tuberculosis (TB). The simple one-step (SOS) stool method …

Background To estimate the diagnostic accuracy of Xpert MTB/RIF for rifampicin resistance
in different regions, a meta-analysis was carried out. Methods Several databases were …

Nucleic acid amplification technologies (NAATs) are high-performance tools for rapidly and
accurately detecting infectious agents. They are widely used in high-income countries to …

Background Aligned with global childhood tuberculosis (TB) road map, Ethiopia developed
its own in 2015. The key strategies outlined in the Ethiopian roadmap are incorporating TB …

One of the key problems in combating TB is the lack of fast and accurate diagnostic tests that
are affordable and easy to use in resource-limited settings. We have used a field-friendly up …

Abstract Background As access to Xpert expands in high TB-burden settings, its
performance against clinically diagnosed TB as a reference standard provides important …

Current diagnostic tests for tuberculosis (TB) are not able to predict reactivation disease
progression from latent TB infection (LTBI). The main barrier to predicting reactivation …