Z Shi, C Miao, UJ Schoepf, RH Savage… - Nature …, 2020 - nature.com
Intracranial aneurysm is a common life-threatening disease. Computed tomography angiography is recommended as the standard diagnosis tool; yet, interpretation can be time …
Introduction: Intravenous administration of tissue-type plasminogen activator (IV-tPA) remains the only approved therapy that may reverse neurological deficit in patients with …
Objective: We sought to determine the safety of IV thrombolysis (IVT) in acute ischemic stroke (AIS) patients harboring unruptured intracranial aneurysm (UIA) in a multicenter study …
A Mowla, K Singh, S Mehla… - … Journal of Stroke, 2015 - journals.sagepub.com
Background Intracranial aneurysms are currently considered as contraindication for intravenous thrombolysis in acute ischemic stroke, very likely due to a possible increase in …
Intravenous (IV) tissue plasminogen activator (tPA), which has convincing evidence in the treatment of acute ischemic stroke, could not be used widely as desired despite the fact that …
D Wen, Y Chen, W Zhu, Z Peng, L Ma - Journal of Neurology, 2023 - Springer
Background For ischemic stroke patients with concomitant unruptured aneurysm, intravenous thrombolysis therapy (IVT) remains a disputable decision. We hence performed …
Y Shono, H Sugimori, R Matsuo… - … Journal of Stroke, 2018 - journals.sagepub.com
Background The safety of antithrombotic therapy for patients with acute ischemic stroke harboring unruptured intracranial aneurysms remains unclear. Aims This study was …
JF Zaldivar-Jolissaint, M Messerer, D Bervini… - Journal of Stroke and …, 2015 - Elsevier
Background Management of ischemic stroke in the presence of aneurysmal brain disease is controversial. Recent retrospective evidence suggests that in selected patients, intravenous …
Background The presence of an intracranial aneurysm is contraindicated to recombinant tissue plasminogen activator (r-tPA) treatment for acute ischemic stroke. However, it is …