Defeating antibiotic-resistant bacteria: exploring alternative therapies for a post-antibiotic era

CH Wang, YH Hsieh, ZM Powers, CY Kao - International journal of …, 2020 - mdpi.com
Antibiotics are one of the greatest medical advances of the 20th century, however, they are
quickly becoming useless due to antibiotic resistance that has been augmented by poor …

Alternatives to antibiotics for the control of bacterial disease in aquaculture

T Defoirdt, P Sorgeloos, P Bossier - Current opinion in microbiology, 2011 - Elsevier
The wide and frequent use of antibiotics in aquaculture has resulted in the development and
spread of antibiotic resistance. Because of the health risks associated with the use of …

Bacterial RNA thermometers: molecular zippers and switches

J Kortmann, F Narberhaus - Nature reviews microbiology, 2012 - nature.com
Bacteria use complex strategies to coordinate temperature-dependent gene expression.
Many genes encoding heat shock proteins and virulence factors are regulated by …

Filamentous bacteriophage: biology, phage display and nanotechnology applications

J Rakonjac, NJ Bennett, J Spagnuolo, D Gagic… - Current issues in …, 2011 - mdpi.com
Filamentous bacteriophage, long and thin filaments that are secreted from the host cells
without killing them, have been an antithesis to the standard view of head-and-tail bacterial …

Engineered toxin–intein antimicrobials can selectively target and kill antibiotic-resistant bacteria in mixed populations

R López-Igual, J Bernal-Bayard… - Nature …, 2019 - nature.com
Targeted killing of pathogenic bacteria without harming beneficial members of host
microbiota holds promise as a strategy to cure disease and limit both antimicrobial-related …

Vibrio cholerae Biofilms and Cholera Pathogenesis

AJ Silva, JA Benitez - PLoS neglected tropical diseases, 2016 - journals.plos.org
Vibrio cholerae can switch between motile and biofilm lifestyles. The last decades have
been marked by a remarkable increase in our knowledge of the structure, regulation, and …

Outer membrane vesicles of Vibrio cholerae protect and deliver active cholera toxin to host cells via porin-dependent uptake

FG Zingl, HB Thapa, M Scharf, P Kohl, AM Müller… - MBio, 2021 - Am Soc Microbiol
Outer membrane vesicles (OMVs) are an emerging research field due to their multifactorial
composition and involvement in interspecies and intraspecies communication. Recent …

Programmable receptors enable bacterial biosensors to detect pathological biomarkers in clinical samples

HJ Chang, A Zúñiga, I Conejero, PL Voyvodic… - Nature …, 2021 - nature.com
Bacterial biosensors, or bactosensors, are promising agents for medical and environmental
diagnostics. However, the lack of scalable frameworks to systematically program ligand …

Cholera toxin—a foe & a friend

J Sánchez, J Holmgren - Indian Journal of Medical Research, 2011 - journals.lww.com
After De's pivotal demonstration in 1959 of a diarrhoeogenic exo-enterotoxin in cell-free
culture filtrates from Vibrio cholerae (of classical biotype), much insight has been gained …

Vibrio Flagellar Synthesis

MA Echazarreta, KE Klose - Frontiers in cellular and infection …, 2019 - frontiersin.org
Vibrio spp. are highly motile Gram-negative bacteria, ubiquitously found in aquatic
environments. Some Vibrio s are responsible for disease and morbidity of marine …