Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer

PD Cani, BF Jordan - Nature Reviews Gastroenterology & Hepatology, 2018 - nature.com
Overweight and obesity are associated with increased risk of developing metabolic
disorders such as diabetes and cardiovascular diseases. However, besides these metabolic …

The role of gingival fibroblasts in the pathogenesis of periodontitis

A Wielento, KB Lagosz-Cwik… - Journal of Dental …, 2023 - journals.sagepub.com
Gingival fibroblasts (GFs) are essential components of the periodontium, which are
responsible for the maintenance of tissue structure and integrity. However, the physiological …

Metabolic Remodeling, Inflammasome Activation, and Pyroptosis in Macrophages Stimulated by Porphyromonas gingivalis and Its Outer Membrane Vesicles

AJ Fleetwood, MKS Lee, W Singleton… - Frontiers in cellular …, 2017 - frontiersin.org
Porphyromonas gingivalis is one of the bacterial species most closely associated with
periodontitis and can shed large numbers of outer membrane vesicles (OMVs), which are …

Local and Systemic Effects of Porphyromonas gingivalis Infection

WA Chen, Y Dou, HM Fletcher, DS Boskovic - Microorganisms, 2023 - mdpi.com
Porphyromonas gingivalis, a gram-negative anaerobe, is a leading etiological agent in
periodontitis. This infectious pathogen can induce a dysbiotic, proinflammatory state within …

[HTML][HTML] Camellia sinensis: insights on its molecular mechanisms of action towards nutraceutical, anticancer potential and other therapeutic applications

P Chaudhary, D Mitra, PKD Mohapatra… - Arabian Journal of …, 2023 - Elsevier
The Camellia sinensis plant provides a wide diversity of black, green, oolong, yellow, brick
dark, and white tea. Tea is one of the majorly used beverages across the globe, succeeds …

IL-1β and TNF-α play an important role in modulating the risk of periodontitis and Alzheimer's disease

RPH Wang, J Huang, KWY Chan, WK Leung… - Journal of …, 2023 - Springer
Background Systemic activation of the immune system can exert detrimental effects on the
central nervous system. Periodontitis, a chronic disease of the oral cavity, is a common …

[HTML][HTML] Pathogenesis of periodontitis–A potential role for epithelial-mesenchymal transition

SS Saliem, SY Bede, PR Cooper… - … Dental Science Review, 2022 - Elsevier
Epithelial mesenchymal transition (EMT) is a process comprising cellular and molecular
events which result in cells shifting from an epithelial to a mesenchymal phenotype …

The innate host response in caries and periodontitis

J Meyle, H Dommisch, S Groeger… - Journal of clinical …, 2017 - Wiley Online Library
Introduction Innate immunity rapidly defends the host against infectious insults. These
reactions are of limited specificity and exhaust without providing long‐term protection …

Functionalization of bacterial cellulose wound dressings with the antimicrobial peptide ε-poly-L-Lysine

M Fürsatz, M Skog, P Sivlér, E Palm… - Biomedical …, 2018 - iopscience.iop.org
Wound dressings based on bacterial cellulose (BC) can form a soft and conformable
protective layer that can stimulate wound healing while preventing bacteria from entering the …

Microbiota, oral microbiome, and pancreatic cancer

DS Michaud, J Izard - The Cancer Journal, 2014 - journals.lww.com
Only 30% of patients with a diagnosis of pancreatic cancer survive 1 year after the
diagnosis. Progress in understanding the causes of pancreatic cancer has been made …