The bioactive peptides galanin, spexin and kisspeptin have a common ancestral origin and
their pathophysiological roles are increasingly the subject of investigation. Evidence …

Spexin (SPX), also called neuropeptide Q (NPQ), is a novel endogenous neuropeptide.
Spexin gene and protein are widely expressed in central nervous system and peripheral …

Spexin (SPX) is a novel adipokine related to many metabolic effects, such as gastrointestinal
movements, insulin and glucose homeostasis, lipid metabolism and energy balance. This …

Spexin is the most recently discovered member of the galanin/kisspeptin/spexin family of
peptides. This 14-amino acid peptide is highly conserved and is implicated in homeostatic …

The function of the gonadotropin-releasing hormone (GnRH) neuron is critical to maintain
reproductive function and a significant decrease in GnRH can lead to disorders affecting …

Spexin (SPX) is a novel neuropeptide, which was first identified in the human genome using
bioinformatics. Since then, orthologs of human SPX have been identified in mammalian and …

Spexin (SPX) is a 14 amino acid peptide hormone that has pleiotropic functions across
vertebrates, one of which is involvement in the brain-pituitary-gonad axis of fish. SPX (1) has …

Spexin (SPX) is a novel neuropeptide and adipokine negatively correlated with obesity and
insulin resistance. A recent study investigated expression and regulatory function of SPX in …

Spexin (SPX) and galanin (GAL) are two neuropeptides that are phylogenetically related
and have descended from a common ancestral gene. Considerable attention has been …

Spexin (SPX) is a pleiotropic peptide with highly conserved protein sequence from fish to
mammals and its biological actions are mediated by GalR2/GalR3 receptors expressed in …