Explainable AI for CHO cell culture media optimization and prediction of critical quality attribute

N Gangwar, K Balraj, AS Rathore - Applied Microbiology and …, 2024 - Springer
Cell culture media play a critical role in cell growth and propagation by providing a
substrate; media components can also modulate the critical quality attributes (CQAs) …

Leveraging bioanalytical characterization of fractionated monoclonal antibody pools to identify aggregation‐prone and less filterable proteoforms during virus filtration

S Isu, L Vinskus, D Silva, K Cunningham… - Biotechnology …, 2024 - Wiley Online Library
Monoclonal antibodies (mAbs) are an essential class of biotherapeutics. A platform process
is used for mAb development to ensure clinically safe and stable molecules. Regulatory …