Epidemiological studies have consistently shown that regular consumption of whole grain
barley reduces the risk of developing chronic diseases. The presence of barley fiber …

▪ Abstract The study of the epithelium of the adult mammalian intestine touches upon many
modern aspects of biology. The epithelium is in a constant dialogue with the underlying …

Colorectal cancer (CRC) is a major health problem in industrialized countries. Although
inflammation-linked carcinogenesis is a well accepted concept and is often observed within …

Systematic consideration of scientific support is a critical element in developing and,
ultimately, using adverse outcome pathways (AOPs) for various regulatory applications …

The dimethyhydrazine (DMH) or azoxymethane (AOM) model is a well‐established, well‐
appreciated, and widely used model of experimental colon carcinogenesis. It has many …

Colorectal cancer (CRC) ranks among the three most common cancers in terms of both
cancer incidence and cancer‐related deaths in most Western countries. Serrated …

Colorectal cancer is a heterogeneous disease. There are three main pathways to colorectal
cancer: the chromosomal instability pathway, the CpG island methylator phenotype pathway …

This review explores the chief genetic and epigenetic events that promote pathological
progression in colorectal carcinogenesis. This article discusses the molecular and …

Simple Summary This review aims to shed light on the proliferative markers important in the
everyday clinical management of colorectal cancer (CRC), ranging from simple methods of …

The intestinal epithelium is a self‐renewing tissue which represents a unique model for
studying interconnected cellular processes such as proliferation, differentiation, cell …