[HTML][HTML] Preliminary genome wide screening identifies new variants associated with coronary artery disease in Indian population

KG Bhat, VS Guleria, G Rastogi, V Sharma… - American Journal of …, 2022 - ncbi.nlm.nih.gov
Aim: Coronary artery disease (CAD) is a major health problem in developed and developing
nations. Development of CAD involves a complex interaction between genetics and lifestyle …

Telomere length in peripheral blood lymphocytes related to genetic variation in telomerase, prognosis and clinicopathological features in breast cancer patients

M Kroupa, S Rachakonda, V Vymetalkova… - …, 2020 - academic.oup.com
Disruption of telomere length (TL) homeostasis in peripheral blood lymphocytes has been
previously assessed as a potential biomarker of breast cancer (BC) risk. The present study …

Association of telomere length with diabetes mellitus and idiopathic dilated cardiomyopathy in a South Indian population: A pilot study

S Rai, ARS Badarinath, A George, S Sitaraman… - … /Genetic Toxicology and …, 2022 - Elsevier
Telomere shortening has been associated with ageing and with many age-related diseases
including cancer, coronary artery disease, heart failure and diabetes. We sought to …

[HTML][HTML] Theoretical investigation of the pathway-based network of type 2 diabetes mellitus-related genes

XY Zhang, TY He, CY Xu, KF Cao, XS Zhang - The European Physical …, 2023 - Springer
Complex network is an effective approach to studying the characteristics and interactions of
complex systems, which can be used to analyze the core functions and global behavior of …

[HTML][HTML] Identification of polymorphic alleles in TERC and TERT gene reprogramming the telomeres of newborn and legacy with parental health

S Baig, R Hussain, R Imad, MY Rana - Saudi Journal of Biological …, 2024 - Elsevier
Telomere and telomerase genes (TERC and TERT) highlighted many novel genetic
polymorphisms related to common diseases. This study explored the polymorphic alleles of …

[HTML][HTML] MassARRAY-based single nucleotide polymorphism analysis in breast cancer of north Indian population

D Bakshi, A Nagpal, V Sharma, I Sharma, R Shah… - BMC cancer, 2020 - Springer
Abstract Background Breast Cancer (BC) is associated with inherited gene mutations. High
throughput genotyping of BC samples has led to the identification and characterization of …

Shortening of leucocyte telomere length is independently correlated with high body mass index and subcutaneous obesity (predominantly truncal), in Asian Indian …

SP Bhatt, A Misra, RM Pandey… - BMJ Open Diabetes …, 2022 - drc.bmj.com
Introduction Leucocyte telomere length (LTL) is linked to accelerate aging and premature
mortality. In this research, we aimed to explore the relations between biochemical and …

[HTML][HTML] Terc Gene Cluster Variants Predict Liver Telomere Length in Mice

D Zeid, S Mooney-Leber, LR Seemiller, LR Goldberg… - Cells, 2021 - mdpi.com
Variants in a gene cluster upstream-adjacent to TERC on human chromosome 3, which
includes genes APRM, LRRC31, LRRC34 and MYNN, have been associated with telomere …

[HTML][HTML] Parental telomeres implications on immune senescence of newborns

S Farrukh, S Baig - American Journal of Clinical and Experimental …, 2023 - ncbi.nlm.nih.gov
Telomere, the biological chronometer, and its effect on the immune system considerably
varies among individuals. During pregnancy, multiple risk factors affect telomere …

[HTML][HTML] The leukocyte telomere length, single nucleotide polymorphisms near TERC gene and risk of COPD

T Tacheva, S Zienolddiny, D Dimov, D Vlaykova… - PeerJ, 2021 - peerj.com
Chronic obstructive pulmonary disease (COPD) is characterized by irreversible airflow
obstruction and is associated with chronic local and systemic inflammation and oxidative …