Estimating the effects of variants found in disease driver genes opens the door to
personalized therapeutic opportunities. Clinical associations and laboratory experiments …

Lung cancer is a major public health problem and a leading cause of cancer-related deaths
worldwide. Despite advances in treatment options, the five-year survival rate for lung cancer …

Background Cisplatin (CDDP) is a mainstay treatment for advanced head and neck
squamous cell carcinomas (HNSCC) despite a high frequency of innate and acquired …

Air pollutants are increasingly emitted into the atmosphere because of the high dependency
of humans on fossil-derived fuels. Wind speed and direction assisted high dispersibility and …

Discovering rare cancer driver genes is difficult because their mutational frequency is too
low for statistical detection by computational methods. EPIMUTESTR is an integrative …

Background Coronary artery disease is a primary cause of death around the world, with both
genetic and environmental risk factors. Although genome‐wide association studies have …

de Magalhães has shown recently that most human genes have several papers in PubMed
mentioning cancer, leading the author to suggest that every gene is associated with cancer …

Objective. Image texture features, such as those derived by Haralick et al, are a powerful
metric for image classification and are used across fields including cancer research. Our aim …

Objective The calculation of texture features, such as those derived by Haralick et al., has
been traditionally limited to 2D-imaging data. We present the novel derivation of an …

Identifying genes involved in disease pathology has been a goal of genomic research since
the early days of the field. However, as technology improves and the body of research …