[HTML][HTML] ETS Transcription Factors in Immune Cells and Immune-Related Diseases
Y Yang, X Han, L Sun, F Shao, Y Yin… - International Journal of …, 2024 - mdpi.com
The development, differentiation, and function of immune cells are precisely regulated by
transcription factors. The E26 transformation-specific (ETS) transcription factor family is …
transcription factors. The E26 transformation-specific (ETS) transcription factor family is …
Role of the RNA binding protein IGF2BP1 in cancer multidrug resistance
AM Gola, M Bucci-Muñoz, JP Rigalli… - Biochemical …, 2024 - Elsevier
The insulin-like growth factor-2 mRNA-binding protein 1 (IGF2BP1), a member of a
conserved family of single-stranded RNA-binding proteins (IGF2BP1-3), is expressed in a …
conserved family of single-stranded RNA-binding proteins (IGF2BP1-3), is expressed in a …
[HTML][HTML] Fusion genes in cancers: Biogenesis, functions, and therapeutic implications
H Tang, Q Peng, L Oyang, S Tan, X Jiang, Z Ren, X Xu… - Genes & …, 2025 - Elsevier
The processes of tumorigenesis and development are intricate, involving numerous genes
and molecular pathways. Fusion genes, direct products of abnormal chromosomal …
and molecular pathways. Fusion genes, direct products of abnormal chromosomal …
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) in hematological diseases
S Ma, Y Qin, W Ren - Molecular Medicine, 2024 - Springer
The oncofetal mRNA-binding protein IGF2BP1 belongs to a conserved family of RNA-
binding proteins. It primarily promotes RNA stability, regulates translation and RNA …
binding proteins. It primarily promotes RNA stability, regulates translation and RNA …
Inflammation as a driver of hematological malignancies
S Saluja, I Bansal, R Bhardwaj, MS Beg… - Frontiers in …, 2024 - frontiersin.org
Hematopoiesis is a tightly regulated process that produces all adult blood cells and immune
cells from multipotent hematopoietic stem cells (HSCs). HSCs usually remain quiescent, and …
cells from multipotent hematopoietic stem cells (HSCs). HSCs usually remain quiescent, and …
Insulin-like Growth Factor II mRNA-Binding Protein 1 Regulates Pancreatic Cancer Cell Growth through the Surveillance of CDC25A mRNA
D Di Fusco, MT Segreto, G Di Maggio, A Iannucci… - Cancers, 2023 - mdpi.com
Simple Summary The progression of PDAC is also regulated at the transcription/
transduction stage. RNA metabolism is manipulated by different RNA-binding proteins …
transduction stage. RNA metabolism is manipulated by different RNA-binding proteins …
Aberrant stem cell and developmental programs in pediatric leukemia
RE Ling, JW Cross, A Roy - Frontiers in Cell and Developmental …, 2024 - frontiersin.org
Hematopoiesis is a finely orchestrated process, whereby hematopoietic stem cells give rise
to all mature blood cells. Crucially, they maintain the ability to self-renew and/or differentiate …
to all mature blood cells. Crucially, they maintain the ability to self-renew and/or differentiate …
LINC00513 promotes colorectal cancer malignant progression by binding with IGF2BP1 to enhance the stability of connective tissue growth factor mRNA
W Lun, X Zhang, Y Hong, C Luo, Y Liu - Epigenomics, 2024 - Taylor & Francis
Aim: This study aimed to investigate the role of LINC00513 in colorectal cancer (CRC)
progression. Materials & methods: Cell proliferation was evaluated using Cell Counting Kit …
progression. Materials & methods: Cell proliferation was evaluated using Cell Counting Kit …
IGF2BP1 facilitates non-small cell lung cancer progression by regulating the KIF2A-mediated Wnt/β-catenin pathway
M Sun, L Wang, L Ge, D Xu, R Zhang - Functional & Integrative Genomics, 2024 - Springer
Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) are crucially implicated in the
cancer progression. The current study intends to excavate and clarify the mechanisms of the …
cancer progression. The current study intends to excavate and clarify the mechanisms of the …
The Diverse Roles of ETV6 Alterations in B-Lymphoblastic Leukemia and Other Hematopoietic Cancers
Genetic alterations of the repressive ETS family transcription factor gene ETV6 are recurrent
in several categories of hematopoietic malignancy, including subsets of B-cell and T-cell …
in several categories of hematopoietic malignancy, including subsets of B-cell and T-cell …