Targeting lncRNA/Wnt axis by flavonoids: A promising therapeutic approach for colorectal cancer
S Han, Y Cao, T Guo, Q Lin, F Luo - Phytotherapy Research, 2022 - Wiley Online Library
Despite the dramatic advances in our understanding of the etiology of colorectal cancer
(CRC) in recent decades, effective therapeutic strategies are still urgently needed …
(CRC) in recent decades, effective therapeutic strategies are still urgently needed …
[HTML][HTML] Wingless/It/β-catenin signaling in liver metastasis from colorectal cancer: A focus on biological mechanisms and therapeutic opportunities
F Selvaggi, T Catalano, R Lattanzio… - World Journal of …, 2023 - ncbi.nlm.nih.gov
The liver is the most common site of metastases in patients with colorectal cancer. Colorectal
liver metastases (CRLMs) are the result of molecular mechanisms that involve different cells …
liver metastases (CRLMs) are the result of molecular mechanisms that involve different cells …
Inhibition of PORCN blocks Wnt signaling to attenuate progression of oral carcinogenesis
Purpose: Oral squamous cell carcinoma (OSCC) is commonly preceded by potentially
malignant lesions, referred to as oral dysplasia. We recently reported that oral dysplasia is …
malignant lesions, referred to as oral dysplasia. We recently reported that oral dysplasia is …
Colorectal cancer immunotherapy: state of the art and future directions
Cancer immunotherapy has become an indispensable mode of treatment for a multitude of
solid tumor cancers. Colorectal cancer (CRC) has been one of the many cancer types to …
solid tumor cancers. Colorectal cancer (CRC) has been one of the many cancer types to …
Transcriptome analysis of the anti-proliferative effects of ginsenoside Rh3 on HCT116 colorectal cancer cells
S Teng, X Lei, X Zhang, D Shen, Q Liu, Y Sun, Y Wang… - Molecules, 2022 - mdpi.com
The mechanism of ginsenoside Rh3 activity against cancer remains unclear. This study
aimed to investigate the underlying mechanism. The effects of Rh3 on the cell proliferation …
aimed to investigate the underlying mechanism. The effects of Rh3 on the cell proliferation …
Intracellular domain of epithelial cell adhesion molecule induces Wnt receptor transcription to promote colorectal cancer progression
SS Panda, CC Lee, K Geevimaan, KC Chen… - Journal of Biomedical …, 2024 - Springer
Background Epithelial cell adhesion molecule (EpCAM) has been widely studied as a tumor
antigen due to its expression in varieties of solid tumors. Moreover, the glycoprotein …
antigen due to its expression in varieties of solid tumors. Moreover, the glycoprotein …
Mechanistic Clues Provided by Concurrent Changes in the Expression of Genes Encoding the M1 Muscarinic Receptor, β-Catenin Signaling Proteins, and …
M Alizadeh, A Schledwitz, K Cheng… - Frontiers in …, 2022 - frontiersin.org
Muscarinic receptors (MRs) in the G protein-coupled receptor superfamily are recipients and
mediators of parasympathetic neural transmission within the central and enteric nervous …
mediators of parasympathetic neural transmission within the central and enteric nervous …
Intravital imaging of Wnt/β-catenin and ATF2-dependent signalling pathways during tumour cell invasion and metastasis
K Stoletov, S Sanchez, I Gorroño… - Journal of Cell …, 2023 - journals.biologists.com
Wnt signalling has been implicated as a driver of tumour cell metastasis, but less is known
about which branches of Wnt signalling are involved and when they act in the metastatic …
about which branches of Wnt signalling are involved and when they act in the metastatic …
[PDF][PDF] NARRATIVE REVIEWS
Cancer immunotherapy has become an indispensable mode of treatment for a multitude of
solid tumor cancers. Colorectal cancer (CRC) has been one of the many cancer types to …
solid tumor cancers. Colorectal cancer (CRC) has been one of the many cancer types to …