Background Propofol is one of the most widely used injectable anaesthetic agents in
veterinary practice. Cardiovascular effects related to propofol use in dogs remain less well …

Sedation and anesthesia alter the raw electroencephalogram (EEG). Interpretation of the
EEG is facilitated by measuring the patient state index (PSI), visual inspection of density …

General anaesthesia in horses is associated with elevated mortality rate in subjects suffering
of heaves. Target-controlled infusion (TCI) of sedative–hypnotic medications and opioids …

An understanding of clinical pharmacology is fundamental to the practice of veterinary
anesthesia and pain management. This chapter introduces classical and receptor state …

Lee, S.‐H., Park, H.‐W., Kim, M.‐J., Noh, M.‐H., Yoon, H.‐S., Choi, B.‐M., Lee, E.‐K., Noh, G.‐
J. External validation of pharmacokinetic and pharmacodynamic models of microemulsion …

Objective To develop a population pharmacokinetic model for propofol target-controlled
infusion (TCI) in dogs and to evaluate its performance for use in the clinical setting. Study …

The aim of this study was to develop and evaluate a pharmacokinetic model‐driven infusion
of propofol in premedicated cats. In a first step, propofol (10 mg/kg) was administered …

The growing interests in propofol as an intravenous anesthetic agent and in particular to its
use in rabbits were the motivation for this work. The rabbit is the third most common pet, and …

Objective To evaluate if the cerebral state index (CSI), measured by a Cerebral State
Monitor (CSM), can predict depth of anaesthesia as assessed clinically or by estimated …

Hypnotic drug administration causes alterations in the electroencephalogram (EEG) in a
dose-dependent manner. These changes cannot be identified easily in the raw EEG …