The role of JAK/STAT signaling pathway and its inhibitors in diseases
P Xin, X Xu, C Deng, S Liu, Y Wang, X Zhou… - International …, 2020 - Elsevier
The JAK/STAT signaling pathway is an universally expressed intracellular signal
transduction pathway and involved in many crucial biological processes, including cell …
transduction pathway and involved in many crucial biological processes, including cell …
COVID-19: manifestações clínicas e laboratoriais na infecção pelo novo coronavírus
RESUMO COVID-19 é uma doença altamente contagiosa provocada pelo coronavírus da
síndrome respiratória aguda grave 2 (SARS-CoV-2). Em 2020, devido ao surto, foi …
síndrome respiratória aguda grave 2 (SARS-CoV-2). Em 2020, devido ao surto, foi …
[HTML][HTML] COVID-19: clinical and laboratory manifestations in novel coronavirus infection
ABSTRACT COVID-19 is a highly contagious disease caused by the coronavirus of severe
acute respiratory syndrome 2 (SARS-CoV-2). In 2020, due to the outbreak, it was considered …
acute respiratory syndrome 2 (SARS-CoV-2). In 2020, due to the outbreak, it was considered …
Paclitaxel alleviated sepsis-induced acute lung injury by activating MUC1 and suppressing TLR-4/NF-κB pathway
YM Wang, R Ji, WW Chen, SW Huang… - Drug Design …, 2019 - Taylor & Francis
Purpose It has been reported that approximately 40% of ALI (acute lung injury) incidence
resulted from sepsis. Paclitaxel, as a classic anti-cancer drug, plays an important role in the …
resulted from sepsis. Paclitaxel, as a classic anti-cancer drug, plays an important role in the …
Inflammation-targeting polymeric nanoparticles deliver sparfloxacin and tacrolimus for combating acute lung sepsis
Y Yang, Y Ding, B Fan, Y Wang, Z Mao, W Wang… - Journal of Controlled …, 2020 - Elsevier
Sepsis is a complex disorder with very high morbidity and mortality; it can occur when an
immune disorder triggers an invasion of pathogens in the host. Although many potential anti …
immune disorder triggers an invasion of pathogens in the host. Although many potential anti …
Therapeutic targets and signaling mechanisms of vitamin C activity against sepsis: a bioinformatics study
R Li, C Guo, Y Li, Z Qin, W Huang - Briefings in bioinformatics, 2021 - academic.oup.com
Sepsis is a life-threatening complication of pneumonia, including coronavirus disease-2019
(COVID-19)-induced pneumonia. Evidence of the benefits of vitamin C (VC) for the treatment …
(COVID-19)-induced pneumonia. Evidence of the benefits of vitamin C (VC) for the treatment …
Severe acute pancreatitis: capillary permeability model linking systemic inflammation to multiorgan failure
NL Komara, P Paragomi, PJ Greer… - American Journal …, 2020 - journals.physiology.org
Severe acute pancreatitis (SAP) includes persistent systemic inflammation (SIRS) and
multiorgan failure (MOF). The mechanism of transition from SIRS to MOF is unclear. We …
multiorgan failure (MOF). The mechanism of transition from SIRS to MOF is unclear. We …
microRNA-27b shuttled by mesenchymal stem cell-derived exosomes prevents sepsis by targeting JMJD3 and downregulating NF-κB signaling pathway
J Sun, X Sun, J Chen, X Liao, Y He, J Wang… - Stem cell research & …, 2021 - Springer
Abstract Background Exosomal microRNAs (miRs) derived from mesenchymal stem cells
(MSCs) have been shown to play roles in the pathophysiological processes of sepsis …
(MSCs) have been shown to play roles in the pathophysiological processes of sepsis …
Postoperative sepsis after colorectal surgery: a prospective single-center observational study and review of the literature
Results A total of 69 males and 72 females were enrolled. Postoperative sepsis was
diagnosed in 18 (12.77%) cases, with anastomotic leakage being the most frequent cause …
diagnosed in 18 (12.77%) cases, with anastomotic leakage being the most frequent cause …
Autophagy suppresses ferroptosis by degrading TFR1 to alleviate cognitive dysfunction in mice with SAE
L Du, Y Wu, Q Jia, J Li, Y Li, H Ma, Z Fan, X Guo… - Cellular and molecular …, 2023 - Springer
Sepsis-associated encephalopathy (SAE) is a serious complication of sepsis that is
characterized by long-term cognitive impairment, which imposes a heavy burden on families …
characterized by long-term cognitive impairment, which imposes a heavy burden on families …