Newly synthesized secretory cargo molecules pass through the Golgi apparatus while
resident Golgi proteins remain in the organelle. However, the pathways of membrane traffic …

Since its first visualization in 1898, the Golgi has been a topic of intense morphological
research. A typical mammalian Golgi consists of a pile of stapled cisternae, the Golgi stack …

The molecular machinery responsible for the generation of transport carriers moving from
the Golgi complex to the plasma membrane relies on a tight interplay between proteins and …

We report that microtubule (MT) nucleation at the Golgi apparatus requires AKAP450, a
centrosomal γ‐TuRC‐interacting protein that also forms a distinct network associated with …

The Golgi is a dynamic organelle whose correct assembly is crucial for cellular homeostasis.
Perturbations in Golgi structure are associated with numerous disorders from …

In addition to the classical functions of the Golgi in membrane transport and glycosylation,
the Golgi apparatus of mammalian cells is now recognised to contribute to the regulation of …

Newly synthesized proteins exit the endoplasmic reticulum (ER) via coat protein complex II
(COPII) vesicles. Procollagen (PC), however, forms prefibrils that are too large to fit into …

The Golgi apparatus lies at the heart of the secretory pathway where it is required for
secretory trafficking and cargo modification. Disruption of Golgi architecture and function has …

The mammalian Golgi apparatus is characterized by a ribbon-like organization adjacent to
the centrosome during interphase and extensive fragmentation and dispersal away from the …

The Golgi apparatus represents a central compartment of membrane traffic. Its apparent
architecture, however, differs considerably among species, from unstacked and scattered …