Pharmacological potential of tocotrienols: a review

H Ahsan, A Ahad, J Iqbal, WA Siddiqui - Nutrition & metabolism, 2014 - Springer
Tocotrienols, members of the vitamin E family, are natural compounds found in a number of
vegetable oils, wheat germ, barley, and certain types of nuts and grains. Like tocopherols …

Tocotrienols, the vitamin E of the 21st century: its potential against cancer and other chronic diseases

BB Aggarwal, C Sundaram, S Prasad… - Biochemical …, 2010 - Elsevier
Initially discovered in 1938 as a “fertility factor,” vitamin E now refers to eight different
isoforms that belong to two categories, four saturated analogues (α, β, γ, and δ) called …

Vitamin E and its anticancer effects

A Abraham, AJ Kattoor, T Saldeen… - Critical reviews in food …, 2019 - Taylor & Francis
Vitamin E is a lipid soluble vitamin comprising of eight natural isoforms, namely, α, β, δ, γ
isoforms of tocopherol and α, β, δ, γ isoforms of tocotrienol. Many studies have been …

Tocotrienols in health and disease: the other half of the natural vitamin E family

CK Sen, S Khanna, S Roy - Molecular aspects of medicine, 2007 - Elsevier
Tocochromanols encompass a group of compounds with vitamin E activity essential for
human nutrition. Structurally, natural vitamin E includes eight chemically distinct molecules …

Cancer-preventive activities of tocopherols and tocotrienols

J Ju, SC Picinich, Z Yang, Y Zhao, N Suh… - …, 2010 - academic.oup.com
The cancer-preventive activity of vitamin E has been studied. Whereas some
epidemiological studies have suggested a protective effect of vitamin E against cancer …

Tocotrienols: The promising analogues of vitamin E for cancer therapeutics

BL Sailo, K Banik, G Padmavathi, M Javadi… - Pharmacological …, 2018 - Elsevier
Despite the significant advancements in the diagnosis and treatment of cancer, it still
remains one of the most fatal diseases in the world due to the lack of sensitive diagnosis …

Vitamin E and cancer: An insight into the anticancer activities of vitamin E isomers and analogs

C Constantinou, A Papas… - International journal of …, 2008 - Wiley Online Library
Current observations in the literature suggest that vitamin E may be a suitable candidate for
the adjuvant treatment of cancer. Even though historically most research focused on α …

Revisiting the therapeutic potential of tocotrienol

R Ranasinghe, M Mathai, A Zulli - Biofactors, 2022 - Wiley Online Library
The therapeutic potential of the tocotrienol group stems from its nutraceutical properties as a
dietary supplement. It is largely considered to be safe when consumed at low doses for …

Tocotrienols fight cancer by targeting multiple cell signaling pathways

R Kannappan, SC Gupta, JH Kim, BB Aggarwal - Genes & nutrition, 2012 - Springer
Cancer cells are distinguished by several distinct characteristics, such as self-sufficiency in
growth signal, resistance to growth inhibition, limitless replicative potential, evasion of …

Tocotrienols: the emerging face of natural vitamin E

CK Sen, S Khanna, C Rink, S Roy - Vitamins & Hormones, 2007 - Elsevier
Natural vitamin E includes eight chemically distinct molecules: α‐, β‐, γ‐, and δ‐tocopherols
and α‐, β‐, γ‐, and δ‐tocotrienols. More than 95% of all studies on vitamin E are directed …