[HTML][HTML] Epidemiology of ovarian cancer: a review

BM Reid, JB Permuth, TA Sellers - Cancer biology & medicine, 2017 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the
world and the tenth most common in China. Epithelial OC is the most predominant …

Systems biology based drug repositioning for development of cancer therapy

B Turanli, O Altay, J Borén, H Turkez, J Nielsen… - Seminars in cancer …, 2021 - Elsevier
Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

Potential biomarkers and therapeutic targets in cervical cancer: Insights from the meta-analysis of transcriptomics data within network biomedicine perspective

M Kori, K Yalcin Arga - PLoS One, 2018 - journals.plos.org
The malignant neoplasm of the cervix, cervical cancer, has effects on the reproductive tract.
Although infection with oncogenic human papillomavirus is essential for cervical cancer …

Evaluation of the p53 pathway in polycystic ovarian syndrome pathogenesis and apoptosis enhancement in human granulosa cells through transcriptome data …

M Zanjirband, R Hodayi, Z Safaeinejad… - Scientific Reports, 2023 - nature.com
The polycystic ovarian syndrome (PCOS) is closely associated with enhanced apoptosis of
granulosa cells, which have a vital role in maturation of oocytes. p53 plays a critical role in …

Network-based approach to identify molecular signatures and therapeutic agents in Alzheimer's disease

MR Rahman, T Islam, B Turanli, T Zaman… - … biology and chemistry, 2019 - Elsevier
Alzheimer's disease (AD) is a dynamic degeneration of the brain with progressive dementia.
Considering the uncertainties in its molecular mechanism, in the present study, we …

[HTML][HTML] The epigenetic correlation among ovarian cancer, endometriosis and PCOS: A review

HT PK, L Unnikrishnan, M Pangath… - Critical reviews in …, 2022 - Elsevier
Ovarian cancer is a frequent malignancy that affects a large percentage of women.
Endometriosis is a chronic condition, where there is a production of benign lesions were …

[HTML][HTML] Precision medicine-the golden gate for detection, treatment and prevention of Alzheimer's disease

H Hampel, SE O'Bryant, JI Castrillo… - The journal of …, 2016 - ncbi.nlm.nih.gov
During this decade, breakthrough conceptual shifts have commenced to emerge in the field
of Alzheimer's disease (AD) recognizing risk factors and the non-linear dynamic continuum …

Identification of prognostic biomarker signatures and candidate drugs in colorectal cancer: insights from systems biology analysis

MR Rahman, T Islam, E Gov, B Turanli, G Gulfidan… - Medicina, 2019 - mdpi.com
Background and objectives: Colorectal cancer (CRC) is the second most common cause of
cancer-related death in the world, but early diagnosis ameliorates the survival of CRC. This …

Differential co-expression analysis reveals a novel prognostic gene module in ovarian cancer

E Gov, KY Arga - Scientific reports, 2017 - nature.com
Ovarian cancer is one of the most significant disease among gynecological disorders that
women suffered from over the centuries. However, disease-specific and effective biomarkers …

Systems biomarkers for papillary thyroid cancer prognosis and treatment through multi-omics networks

G Gulfidan, M Soylu, D Demirel, HBC Erdonmez… - Archives of biochemistry …, 2022 - Elsevier
The identification of biomolecules associated with papillary thyroid cancer (PTC) has upmost
importance for the elucidation of the disease mechanism and the development of effective …