Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration

B Grimmig, SH Kim, K Nash, PC Bickford… - Geroscience, 2017 - Springer
Astaxanthin (AXT) is a carotenoid with multiple health benefits. It is currently marketed as a
health supplement and is well known for its antioxidant capacity. Recent evidence has …

The neuroprotective effects of astaxanthin: therapeutic targets and clinical perspective

S Fakhri, I Yosifova Aneva, MH Farzaei… - Molecules, 2019 - mdpi.com
As the leading causes of human disability and mortality, neurological diseases affect
millions of people worldwide and are on the rise. Although the general roles of several …

Preclinical models for Alzheimer's disease: past, present, and future approaches

A Akhtar, SM Gupta, S Dwivedi, D Kumar… - ACS …, 2022 - ACS Publications
A robust preclinical disease model is a primary requirement to understand the underlying
mechanisms, signaling pathways, and drug screening for human diseases. Although various …

Dietary prospects of coconut oil for the prevention and treatment of Alzheimer's disease (AD): A review of recent evidences

SV Ramesh, V Krishnan, S Praveen… - Trends in Food Science & …, 2021 - Elsevier
Background Alzheimer's disease (AD) is a devastating neurodegenerative ailment having
pathological hallmarks of plaques due to amyloid β (Aβ) peptides and neurofibrillary tangles …

Effects of vanillic acid on Aβ1-40-induced oxidative stress and learning and memory deficit in male rats

N Ahmadi, S Safari, N Mirazi, SA Karimi, A Komaki - Brain research bulletin, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease, in which the accumulation of β-
amyloid (Aβ) peptide in the extracellular space causes a progressive reduction in cognitive …

Investigation of thymol effect on learning and memory impairment induced by intrahippocampal injection of amyloid beta peptide in high fat diet-fed rats

M Asadbegi, P Yaghmaei, I Salehi, A Komaki… - Metabolic brain …, 2017 - Springer
Obesity and consumption of a high fat diet (HFD) are known to increase the risk of
Alzheimer's disease (AD). In the present study, we have examined the protective and …

[HTML][HTML] Investigation of the protective effects of lutein on memory and learning using behavioral methods in a male rat model of Alzheimer's disease

L Nazari, S Komaki, I Salehi, S Raoufi… - Journal of Functional …, 2022 - Elsevier
Oxidative stress plays an important role in the development of Alzheimer's disease (AD). The
purpose of this study was to investigate the protective effects of lutein, a carotenoid with …

Effects of exposure to extremely low-frequency electromagnetic fields on spatial and passive avoidance learning and memory, anxiety-like behavior and oxidative …

SA Karimi, I Salehi, T Shykhi, S Zare… - Behavioural brain research, 2019 - Elsevier
There are many controversies about the safety of extremely low-frequency electromagnetic
field (ELF-EMF) on body health and cognitive performance. In the present study, we …

Virgin coconut oil (VCO) by normalizing NLRP3 inflammasome showed potential neuroprotective effects in Amyloid-β induced toxicity and high-fat diet fed rat

F Mirzaei, M Khazaei, A Komaki, I Amiri… - Food and Chemical …, 2018 - Elsevier
Both dyslipidemia and Alzheimer disease (AD) are associated with aging. In this study, the
effects of virgin coconut oil (VCO) on inflammasome and oxidative stress in Alzheimer's …

Cardiac tissue oxidative stress and inflammation after vitamin D administrations in high fat-diet induced obese rats

MA Farhangi, G Nameni, G Hajiluian… - BMC cardiovascular …, 2017 - Springer
Background Obesity is associated with numerous metabolic and inflammatory disorders.
The current study was aimed to evaluate the effects of vitamin D administration on the …