[HTML][HTML] Polymeric micelles in drug delivery: An insight of the techniques for their characterization and assessment in biorelevant conditions

M Ghezzi, S Pescina, C Padula, P Santi… - Journal of Controlled …, 2021 - Elsevier
Polymeric micelles, ie aggregation colloids formed in solution by self-assembling of
amphiphilic polymers, represent an innovative tool to overcome several issues related to …

Doxorubicin: nanotechnological overviews from bench to bedside

M Cagel, E Grotz, E Bernabeu, MA Moretton… - Drug discovery today, 2017 - Elsevier
Highlights•Doxorubicin (DOX) is considered one of the most effective chemotherapeutic
agents.•Dose-cumulative cardiotoxicity is the most dangerous adverse effect.•DOX-based …

Current status and challenges of analytical methods for evaluation of size and surface modification of nanoparticle-based drug formulations

Y Takechi-Haraya, T Ohgita, Y Demizu, H Saito… - AAPS …, 2022 - Springer
The present review discusses the current status and difficulties of the analytical methods
used to evaluate size and surface modifications of nanoparticle-based pharmaceutical …

The new era of nanotechnology, an alternative to change cancer treatment

A Jurj, C Braicu, LA Pop, C Tomuleasa… - Drug design …, 2017 - Taylor & Francis
In the last few years, nanostructures have gained considerable interest for the safe delivery
of therapeutic agents. Several therapeutic approaches have been reported, such as …

An integrated assessment of morphology, size, and complement activation of the PEGylated liposomal doxorubicin products Doxil®, Caelyx®, DOXOrubicin, and …

PP Wibroe, D Ahmadvand, MA Oghabian… - Journal of Controlled …, 2016 - Elsevier
In order to improve patient's benefit and safety, comprehensive regulatory guidelines on
specificities of Non-Biological Complex Drugs (NBCDs), such as doxorubicin-encapsulated …

Clinical applications of nanomedicine in cancer therapy

M Norouzi, M Amerian, M Amerian, F Atyabi - Drug discovery today, 2020 - Elsevier
Cancer incidence and mortality are rapidly growing worldwide. In attempts to develop more
efficacious therapeutic regimens for patients with cancer, nanomedicines have found …

Structural characterization of biomaterials by means of small angle X-rays and neutron scattering (SAXS and SANS), and light scattering experiments

D Lombardo, P Calandra, MA Kiselev - Molecules, 2020 - mdpi.com
Scattering techniques represent non-invasive experimental approaches and powerful tools
for the investigation of structure and conformation of biomaterial systems in a wide range of …

Drug nanocrystallisation within liposomes

T Li, D Cipolla, T Rades, BJ Boyd - Journal of Controlled Release, 2018 - Elsevier
Liposomes are phospholipid bilayer vesicles that have been explored in pharmaceutical
research as drug delivery systems for> 50 years. Despite being important to their …

New insights and evolving role of pegylated liposomal doxorubicin in cancer therapy

AA Gabizon, Y Patil, NM La-Beck - Drug Resistance Updates, 2016 - Elsevier
We herein review various pharmacological and clinical aspects of pegylated liposomal
doxorubicin (PLD), the first nanomedicine to be approved for cancer therapy, and discuss …

[HTML][HTML] Size measurement of extracellular vesicles and synthetic liposomes: the impact of the hydration shell and the protein corona

Z Varga, B Fehér, D Kitka, A Wacha, A Bóta… - Colloids and Surfaces B …, 2020 - Elsevier
Size characterization of extracellular vesicles (EVs) and drug delivery liposomes is of great
importance in their applications in diagnosis and therapy of diseases. There are many …