Liquid biopsies: Potential and challenges

I Heidrich, L Ačkar… - … Journal of Cancer, 2021 - Wiley Online Library
The analysis of tumor cells or tumor cell products obtained from blood or other body fluids
(“liquid biopsy”[LB]) provides a broad range of opportunities in the field of oncology. Clinical …

Biomarkers for prostate cancer: prostate-specific antigen and beyond

MJ Duffy - Clinical Chemistry and Laboratory Medicine (CCLM), 2020 - degruyter.com
In recent years, several new biomarkers supplementing the role of prostate-specific antigen
(PSA) have become available for men with prostate cancer. Although widely used in an ad …

[HTML][HTML] Methylation biomarkers for early cancer detection and diagnosis: Current and future perspectives

J Ibrahim, M Peeters, G Van Camp… - European Journal of …, 2023 - Elsevier
The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies

C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

[HTML][HTML] Microbiomes of urine and the prostate are linked to human prostate cancer risk groups

R Hurst, E Meader, A Gihawi, G Rallapalli… - European urology …, 2022 - Elsevier
Background Bacteria play a suspected role in the development of several cancer types, and
associations between the presence of particular bacteria and prostate cancer have been …

Beyond liquid biopsy: Toward non-invasive assays for distanced cancer diagnostics in pandemics

F Ferrara, S Zoupanou, E Primiceri, Z Ali… - Biosensors and …, 2022 - Elsevier
Liquid biopsy technologies have seen a significant improvement in the last decade, offering
the possibility of reliable analysis and diagnosis from several biological fluids. The use of …

Clinical relevance of circulating tumor cells in prostate cancer management

WA Cieślikowski, A Antczak, M Nowicki, M Zabel… - Biomedicines, 2021 - mdpi.com
Given the low specificity of the routinely used biomarker prostate-specific antigen, circulating
tumor cell (CTC) enumeration seems to be particularly useful in the monitoring of prostate …

Liquid biopsy in diagnosis and prognosis of non-metastatic prostate cancer

AS Rzhevskiy, AY Kapitannikova, DV Butnaru… - Biomedicines, 2022 - mdpi.com
Currently, sensitive and specific methods for the detection and prognosis of early stage PCa
are lacking. To establish the diagnosis and further identify an appropriate treatment strategy …

Biomarkers for the Detection and Risk Stratification of Aggressive Prostate Cancer

S Eickelschulte, AL Riediger, AK Angeles, F Janke… - Cancers, 2022 - mdpi.com
Simple Summary Prostate cancer is a heterogeneous disease and a major cause of cancer
deaths worldwide. The most widely used prostate cancer biomarker, prostate-specific …

Advances in prognostic methylation biomarkers for prostate cancer

D Lam, S Clark, C Stirzaker, R Pidsley - Cancers, 2020 - mdpi.com
Simple Summary Prostate cancer is a major cause of cancer-related death in men
worldwide. There is an urgent clinical need for improved prognostic biomarkers to better …