Starvation Responses Throughout the Caenorhabditis elegans Life Cycle
Caenorhabditis elegans survives on ephemeral food sources in the wild, and the species
has a variety of adaptive responses to starvation. These features of its life history make the …
has a variety of adaptive responses to starvation. These features of its life history make the …
[HTML][HTML] The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogaster
Insulin/insulin-like growth factor (IGF)-1 signaling (IIS) pathway regulates aging in many
organisms, ranging from simple invertebrates to mammals, including humans. Many seminal …
organisms, ranging from simple invertebrates to mammals, including humans. Many seminal …
WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data
The emergence of large gene expression datasets has revealed the need for improved tools
to identify enriched gene categories and visualize enrichment patterns. While gene …
to identify enriched gene categories and visualize enrichment patterns. While gene …
Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression
R Kaletsky, V Yao, A Williams, AM Runnels… - PLoS …, 2018 - journals.plos.org
The biology and behavior of adults differ substantially from those of developing animals, and
cell-specific information is critical for deciphering the biology of multicellular animals. Thus …
cell-specific information is critical for deciphering the biology of multicellular animals. Thus …
Using networks to measure similarity between genes: association index selection
Biological networks can be used to functionally annotate genes on the basis of interaction-
profile similarities. Metrics known as association indices can be used to quantify interaction …
profile similarities. Metrics known as association indices can be used to quantify interaction …
Natural genetic variation drives microbiome selection in the Caenorhabditis elegans gut
Host genetic landscapes can shape microbiome assembly in the animal gut by contributing
to the establishment of distinct physiological environments. However, the genetic …
to the establishment of distinct physiological environments. However, the genetic …
The African turquoise killifish: A research organism to study vertebrate aging and diapause
The African turquoise killifish has recently gained significant traction as a new research
organism in the aging field. Our understanding of aging has strongly benefited from …
organism in the aging field. Our understanding of aging has strongly benefited from …
An overview of the insulin signaling pathway in model organisms Drosophila melanogaster and Caenorhabditis elegans
SG Biglou, WG Bendena, I Chin-Sang - Peptides, 2021 - Elsevier
The insulin/insulin-like growth factor signaling pathway is an evolutionary conserved
pathway across metazoans and is required for development, metabolism and behavior. This …
pathway across metazoans and is required for development, metabolism and behavior. This …
C. elegans and its bacterial diet as a model for systems-level understanding of host–microbiota interactions
Highlights•C. elegans and its bacterial diet is an excellent model system for mammalian host–
microbiota interactions.•C. elegans carries a distinct and species-rich microbiome.• …
microbiota interactions.•C. elegans carries a distinct and species-rich microbiome.• …
A functional study of all 40 Caenorhabditis elegans insulin-like peptides
S Zheng, H Chiu, J Boudreau, T Papanicolaou… - Journal of Biological …, 2018 - ASBMB
The human genome encodes 10 insulin-like genes, whereas the Caenorhabditis elegans
genome remarkably encodes 40 insulin-like genes. Knockout strategies to determine the …
genome remarkably encodes 40 insulin-like genes. Knockout strategies to determine the …