MicroRNA regulation of RNA virus replication and pathogenesis

DW Trobaugh, WB Klimstra - Trends in molecular medicine, 2017 - cell.com
microRNAs (miRNAs) are non-coding RNAs that regulate many processes within a cell by
manipulating protein levels through direct binding to mRNA and influencing translation …

LncRNA, miRNA and lncRNA-miRNA interaction in viral infection

L Chen, Y Zhou, H Li - Virus research, 2018 - Elsevier
Noncoding RNAs (ncRNAs) are key components of the transcriptome and play an important
role in both normal biological activity and pathological processes such as viral infection and …

MicroRNA-155 and antiviral immune responses

A Jafarzadeh, A Naseri, L Shojaie, M Nemati… - International …, 2021 - Elsevier
The microRNA, miR-155 regulates both adaptive and innate immune responses. In viral
infections, miR-155 can affect both innate immunity (interferon response, natural killer cell …

Potential role of cellular miRNAs in coronavirus-host interplay

S Nersisyan, N Engibaryan, A Gorbonos, K Kirdey… - PeerJ, 2020 - peerj.com
Host miRNAs are known as important regulators of virus replication and pathogenesis. They
can interact with various viruses through several possible mechanisms including direct …

[HTML][HTML] lncRNA MEG3 aggravated neuropathic pain and astrocyte overaction through mediating miR-130a-5p/CXCL12/CXCR4 axis

J Dong, R Xia, Z Zhang, C Xu - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Objective: Long non-coding RNAs (lncRNAs) exert a critical function in mediating
neuropathic pain (NP). MEG3, a novel lncRNA, contributes to astrocyte activation and …

Computational analysis of targeting SARS-CoV-2, viral entry proteins ACE2 and TMPRSS2, and interferon genes by host microRNAs

JB Pierce, V Simion, B Icli, D Perez-Cremades… - Genes, 2020 - mdpi.com
Rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus
responsible for coronavirus disease 2019 (COVID-19), has led to a global pandemic …

Contribution of host miRNA-223-3p to SARS-CoV-induced lung inflammatory pathology

L Morales, JC Oliveros, L Enjuanes, I Sola - Mbio, 2022 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus (SARS-CoV) and the closely related SARS-
CoV-2 are emergent highly pathogenic human respiratory viruses causing acute lethal …

Endogenous cellular microRNAs mediate antiviral defense against influenza A virus

S Peng, J Wang, S Wei, C Li, K Zhou, J Hu, X Ye… - … Therapy-Nucleic Acids, 2018 - cell.com
The reciprocal interaction between influenza virus and host microRNAs (miRNAs) has been
implicated in the regulation of viral replication and host tropism. However, the global roles of …

miR-155-3p: processing by-product or rising star in immunity and cancer?

O Dawson, AM Piccinini - Open Biology, 2022 - royalsocietypublishing.org
MicroRNAs (miRNAs) are key players in gene regulation that target specific mRNAs for
degradation or translational repression. Each miRNA is synthesized as a miRNA duplex …

Exosome-delivered and Y RNA-derived small RNA suppresses influenza virus replication

YM Liu, CH Tseng, YC Chen, WY Yu, MY Ho… - Journal of biomedical …, 2019 - Springer
Background Multiple interplays between viral and host factors are involved in influenza virus
replication and pathogenesis. Several small RNAs have recently emerged as important …