New developments in the biology of fibroblast growth factors
DM Ornitz, N Itoh - WIREs mechanisms of disease, 2022 - Wiley Online Library
The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …
The multiple roles of FGF signaling in the developing spinal cord
R Diez del Corral, AV Morales - Frontiers in cell and developmental …, 2017 - frontiersin.org
During vertebrate embryonic development, the spinal cord is formed by the neural
derivatives of a neuromesodermal population that is specified at early stages of …
derivatives of a neuromesodermal population that is specified at early stages of …
Fgf4 maintains Hes7 levels critical for normal somite segmentation clock function
MJ Anderson, V Magidson, R Kageyama… - Elife, 2020 - elifesciences.org
During vertebrate development, the presomitic mesoderm (PSM) periodically segments into
somites, which will form the segmented vertebral column and associated muscle, connective …
somites, which will form the segmented vertebral column and associated muscle, connective …
[HTML][HTML] An FGF3-BMP signaling axis regulates caudal neural tube closure, neural crest specification and anterior-posterior axis extension
During vertebrate axis extension, adjacent tissue layers undergo profound morphological
changes: within the neuroepithelium, neural tube closure and neural crest formation are …
changes: within the neuroepithelium, neural tube closure and neural crest formation are …
The Fgf8 subfamily (Fgf8, Fgf17 and Fgf18) is required for closure of the embryonic ventral body wall
M Boylan, MJ Anderson, DM Ornitz… - …, 2020 - journals.biologists.com
The closure of the embryonic ventral body wall in amniotes is an important morphogenetic
event and is essential for life. Defects in human ventral wall closure are a major class of birth …
event and is essential for life. Defects in human ventral wall closure are a major class of birth …
Primer on FGF3
C Hutchings, D Sela-Donenfeld - Differentiation, 2024 - Elsevier
Though initially discovered as a proto-oncogene in virally induced mouse mammary tumors,
FGF3 is primarily active in prenatal stages, where it is found at various sites at specific times …
FGF3 is primarily active in prenatal stages, where it is found at various sites at specific times …
Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival
L Zelarayan, V Vendrell… - Developmental …, 2022 - Wiley Online Library
Abstract Background Fibroblast growth factors (Fgfs) are required for survival and organ
formation during embryogenesis. Fgfs often execute their functions redundantly. Previous …
formation during embryogenesis. Fgfs often execute their functions redundantly. Previous …
Fgf4 is critical for maintaining Hes7 levels and Notch oscillations in the somite segmentation clock
MJ Anderson, V Magidson, R Kageyama… - BioRxiv, 2020 - biorxiv.org
During vertebrate development, the presomitic mesoderm (PSM) is periodically segmented
into somites, which will form the segmented vertebral column and associated muscle …
into somites, which will form the segmented vertebral column and associated muscle …
[HTML][HTML] HSCs transdifferentiate primarily to pneumonocytes in radiation-induced lung damage repair
L Li, S Zhang, C Ge, L Ji, Y Lv, C Zhao, L Xu… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Accumulative radiation exposure leads to hematopoietic or tissue aging. Whether
hematopoietic stem cells (HSCs) are involved in lung damage repair in response to …
hematopoietic stem cells (HSCs) are involved in lung damage repair in response to …