Studying and modelling dynamic biological processes using time-series gene expression data
Biological processes are often dynamic, thus researchers must monitor their activity at
multiple time points. The most abundant source of information regarding such dynamic …
multiple time points. The most abundant source of information regarding such dynamic …
[HTML][HTML] Dynamics in transcriptomics: advancements in RNA-seq time course and downstream analysis
D Spies, C Ciaudo - Computational and structural biotechnology journal, 2015 - Elsevier
Abstract Analysis of gene expression has contributed to a plethora of biological and medical
research studies. Microarrays have been intensively used for the profiling of gene …
research studies. Microarrays have been intensively used for the profiling of gene …
Wounding triggers callus formation via dynamic hormonal and transcriptional changes
Wounding is a primary trigger of organ regeneration, but how wound stress reactivates cell
proliferation and promotes cellular reprogramming remains elusive. In this study, we …
proliferation and promotes cellular reprogramming remains elusive. In this study, we …
[HTML][HTML] CDK6 levels regulate quiescence exit in human hematopoietic stem cells
Regulated blood production is achieved through the hierarchical organization of dormant
hematopoietic stem cell (HSC) subsets that differ in self-renewal potential and division …
hematopoietic stem cell (HSC) subsets that differ in self-renewal potential and division …
[HTML][HTML] A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells
We report the immediate effects of estrogen signaling on the transcriptome of breast cancer
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …
cells using global run-on and sequencing (GRO-seq). The data were analyzed using a new …
[HTML][HTML] Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish
Background Increasing use of zebrafish in drug discovery and mechanistic toxicology
demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP …
demands knowledge of cytochrome P450 (CYP) gene regulation and function. CYP …
Library preparation methodology can influence genomic and functional predictions in human microbiome research
MB Jones, SK Highlander… - Proceedings of the …, 2015 - National Acad Sciences
Observations from human microbiome studies are often conflicting or inconclusive. Many
factors likely contribute to these issues including small cohort sizes, sample collection, and …
factors likely contribute to these issues including small cohort sizes, sample collection, and …
[HTML][HTML] A hierarchical multi-oscillator network orchestrates the Arabidopsis circadian system
N Takahashi, Y Hirata, K Aihara, P Mas - Cell, 2015 - cell.com
Short-and long-distance circadian communication is essential for integration of temporal
information. However, a major challenge in plant biology is to decipher how individual …
information. However, a major challenge in plant biology is to decipher how individual …
Mev: multiexperiment viewer
Abstract MultiExperiment Viewer (MeV) is a freely available software application that puts
modern bioinformatics tools for integrative data analysis in the hands of bench biologists …
modern bioinformatics tools for integrative data analysis in the hands of bench biologists …
Interplay of microRNAs, transcription factors and target genes: linking dynamic expression changes to function
PV Nazarov, SE Reinsbach, A Muller… - Nucleic acids …, 2013 - academic.oup.com
MicroRNAs (miRNAs) are ubiquitously expressed small non-coding RNAs that, in most
cases, negatively regulate gene expression at the post-transcriptional level. miRNAs are …
cases, negatively regulate gene expression at the post-transcriptional level. miRNAs are …