[HTML][HTML] Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics

Z Payandeh, B Tangruksa, J Synnergren… - Molecular Aspects of …, 2024 - Elsevier
Modern methods of molecular diagnostics and therapy have revolutionized the field of
medicine in recent years by providing more precise and effective tools for detecting and …

[HTML][HTML] Unraveling the Multifaceted Roles of Extracellular Vesicles: Insights into Biology, Pharmacology, and Pharmaceutical Applications for Drug Delivery

A Al-Jipouri, À Eritja, M Bozic - International Journal of Molecular …, 2023 - mdpi.com
Extracellular vesicles (EVs) are nanoparticles released from various cell types that have
emerged as powerful new therapeutic option for a variety of diseases. EVs are involved in …

Dynamic role of exosome microRNAs in cancer cell signaling and their emerging role as noninvasive biomarkers

J Aseervatham - Biology, 2023 - mdpi.com
Simple Summary Exosomes are vesicles that vary between 40 and 150 nm in diameter and
are secreted by cells. These carry miRNAs that have various roles in intercellular signaling …

G× E interactions as a basis for toxicological uncertainty

I Suciu, D Pamies, R Peruzzo, PH Wirtz… - Archives of …, 2023 - Springer
To transfer toxicological findings from model systems, eg animals, to humans, standardized
safety factors are applied to account for intra-species and inter-species variabilities. An …

Development of a robust and generalizable algorithm" gQuant" for accurate normalizer gene selection in qRT-PCR analysis

AK Pathak, S Kural, S Singh, L Kumar, M Yadav… - Scientific Reports, 2024 - nature.com
The emergent role of nucleic acid-based biomarkers—microRNAs (miRNAs), long non-
coding RNAs (lncRNAs), and messenger RNAs (mRNAs), is becoming increasingly …

MicroRNAs as biomarkers for early diagnosis, targeting and prognosis of prostate cancer

A Azani, SP Omran, H Ghasrsaz, A Idani… - … -Research and Practice, 2023 - Elsevier
Globally, prostate cancer (PC) is leading cause of cancer-related mortality in men
worldwide. Despite significant advances in the treatment and management of this disease …

Influential factors on urine EV DNA methylation detection and its diagnostic potential in prostate cancer

T Ding, Y Diao, X Zeng, L Zhou, G Wu, J Liu… - Frontiers in …, 2024 - frontiersin.org
The value of Extracellular vesicles (EVs) diagnostic markers is widely recognized. However,
current research on EV DNA remains limited. This study investigates the biological …

Exosomal miR-664a-5p as a therapeutic target biomarker for PARP inhibitor response in prostate cancer

MY Kim, HW Moon, MS Jo… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
This study investigated the role of urinary exosomal miR-664a-5p as a potential therapeutic
target in prostate cancer (PCa). Small RNA sequencing of urinary exosomes from PCa …

MicroRNA in prostate cancer: from biogenesis to applicative potential

X Luo, W Wen - BMC urology, 2024 - Springer
Prostate cancer is the most common solid malignant tumor in men, characterized by high
morbidity and mortality. While current screening tools, such as prostate-specific antigen …

Liquid biomarkers in prostate cancer: recent advancements and future directions

CHM Wong, ICH Ko, CF Ng - Current Opinion in Urology, 2025 - journals.lww.com
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